We determined that laryngeal cancer was associated with oxidative stress, which may be quantified by measuring 8-hydroxy-2'-deoxyguanosine. For a patient with a suspicious laryngeal lesion, 8-hydroxy-2'-deoxyguanosine levels in blood and urine can provide advance information about the likely diagnosis.

No abstract

Objective: The objective of this study was to evaluate the causes of persistent nasal obstruction of patients after septoplasty. Materials and Methods:After exclusion of allergic rhinitis, nonallergic rhinitis and nasal polyposis, this study included 90 patients with nasal breathing problem who underwent septoplasty at least 4 months ago. After taking full history and completing otorhinological and endoscopic examination, all patients graded their extent of obstruction using the Nasal Obstruction Symptoms Evaluation scale. Results:Our results showed only 45% of patients' persist septal deviation; besides other obstructive pathologies, 55% were detected after detailed otolaryngologic evaluation. Conclusion:Therefore, septal surgeons need to observe all obstructive causes of the nose carefully before planning the procedure.Keywords: Nasal obstruction, septoplasty, endoscopic, rhinitis Özet Amaç: Bu çalışmanın amacı septum cerrahisi geçirmiş olmasına rağ-men burun tıkanıklığı şikayeti devam eden hastalarda buna neden olan durumun veya durumların değerlendirilmesidir. Gereç ve Yöntem:Alerjik rinit, non-alerjik rinit ve nazal polipozis hastalığı olmayan ve septum cerrahisi geçirme hikayesine sahip 90 hasta çalışmaya dahil edildi. Hastalar anamnezleri alınıp otolaringolojik muayeneleri yapıldıktan sonra ''Nasal Obstruction Evaluation'' skalası ile değerlendirildiler. Bulgular:Hastaların %45'inde persiste eden nazal septum deviasyonu saptandı. Diğer %55'inde de obstrüksiyona yapan diğer nedenler gözlemlendi.Sonuç: Sonuç olarak septum cerrahisi ile uğraşan cerrahların ameliyat öncesi obstrüksiyona neden olabilecek tüm nedenleri saptaması ve cerrahi planlamanın buna göre yapılması hastayı ikinci bir nazal cerrahiden koruyacaktır.

Average tumor volumes in patients with stage T3 before and after treatment were 10.12 ± 3.58 cm(3) and 1.33 ± 1.74 cm(3), respectively (p = 0.008). These volumes were 11.92 ± 4.61 cm(3) and 2.17 ± 2.34 cm(3) (p = 0.008) for patients with stage T4, respectively. Post-treatment tumor volumes were statistically reduced compared to pre-treatment volumes in all stages.

Objective: Several types of nasal packs are used postoperatively in septoplasty. In this study, we compared two commonly used nasal packing materials, the intranasal septal splint with airway and Merocel tampon, in terms of pain, bleeding, nasal obstruction, eating difficulties, discomfort in sleep, and pain and bleeding during removal of packing in the early period. Methods:The study group included 60 patients undergoing septoplasty. Patients were divided into two groups (n=30 in each group). An intranasal splint with airway was used for the patients in the first group after septoplasty, while Merocel nasal packing was used for the second group. Patients were investigated in terms of seven different factors -pain, bleeding while the tampon was in place, nasal obstruction, eating difficulties, night sleep, pain during removal of the nasal packing, and bleeding after removal of packing. Results:There was no statistically significant difference between the groups in terms of pain 24 hours after operation (p=0.05), while visual analog scale (VAS) scores for nasal obstruction, night sleep, eating difficulties, and pain during packing removal were lower in the nasal splint group with a statistically significant difference (p<0.05). There was no statistically significant difference between the groups in terms of postoperative bleeding (p=0.23). Significantly less bleeding occurred during removal of the packing in the nasal splint group (p<0.05). Conclusion:Our study indicates that the nasal splint was more comfortable and effective in terms of causing lesser bleeding and pain during removal of packing.