RDW is higher in prehypertensive and hypertensive patients compared with healthy controls independently of age, inflammatory status and anemia. Higher RDW values are strongly correlated with higher systolic and diastolic blood pressures.

No abstract

It has been universally accepted that cervical carcinoma and its closest preinvasive precursor lesion (high-grade cervical intraepithelial neoplasia [CIN] lesions) are caused by a persistent infection with one or more of about 14 high-risk human papillomavirus (hrHPV) types (10, 15). Cervical cancer screening programs rely on the detection and treatment of cervical precancerous (high-grade CIN) lesions and treatable cancer in order to reduce the mortality from this disease. The results of several large population-based randomized screening trials indicate that compared to cytology, testing for about 14 hrHPV types results in marked reductions in the incidence of highgrade CIN lesions and cervical cancers among women who test negative at follow-up (1,4,13,(16)(17)(18). This argues for the implementation of testing for hrHPV in cervical screening programs at increased intervals.The tests for hrHPV that were successfully used in these trials are the commercially available, FDA-approved hrHPV Hybrid Capture 2 assay (hc2) and the consensus primer GP5ϩ/ 6ϩ-PCR with an enzyme immunoassay (EIA) readout (GP5ϩ/ 6ϩ-PCR-EIA) (1,4,13,(16)(17)(18). Both assays target hrHPV types 16,18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, and 68, is additionally targeted by the GP5ϩ/6ϩ-PCR-EIA but is detected by hc2 as a result of cross-hybridization. Given their better performance characteristics relative to those of cytology, these tests can be considered clinically validated for use for cervical screening (14).It has become clear that different assays for hrHPV display different clinical sensitivities and clinical specificities for highgrade CIN lesions and cervical carcinoma (8,9,14,20), and consequently, hrHPV tests different from hc2 and GP5ϩ/ 6ϩ-PCR-EIA are not necessarily useful for cervical screening purposes. In order to facilitate the acceptance and suitability of novel hrHPV assays for cervical screening purposes, guidelines describing the requirements for the use of HPV tests for primary screening have recently been provided by a North American-European collaboration (14). These guidelines propose the use of a clinical validation strategy, based on analysis of the equivalence of the result of an assay relative to that of a clinically validated reference HPV test (i.e., hc2), with samples

Anadolu, tarihsel süreç içerisinde konumu itibariyle birçok medeniyete ve faklı kültürel kimlikteki topluluklara ev sahipliği yapmıştır. Bu toplulukların birçok kültürel üretimleri zamanla değişikliklere uğrasa da günümüze kadar ulaşmış ve çeşitli araştırmalara konu olmuştur. 6. Yüzyıldan bu yana Doğu Karadeniz bölgesinde yaşamlarını sürdüren Hemşinliler de çeşitli araştırmalara konu olmuş topluluklardan birisidir. Hemşinliler; bölgesel, teolojik ve fonolojik açıdan Batı (Rize), Doğu (Artvin) ve Kuzey (Gürcistan, Rusya) olmak üzere 3 farklı grup içerisinde incelenmektedir. Yüksek rakımlı yaylalarda tarım, hayvancılık ve günümüzde turizmle yaşantılarını sürdüren Hemşinlilerin müziksel üretimlerinin uğraşmış oldukları meslek kollarıyla bağlantılı olarak şekillendiği söylenebilir. Bu etnik yapının ve bölgenin müzik kültürü içerisinde görülen tek çalgı tulumdur. Çalgı hakkında yazılı kaynakların kısıtlı sayıda olması bu çalışmanın oluşmasında etkili rol oynamıştır. Hazırlanan bu çalışma 2017 yılında tarafımca hazırlanan "Rize Çamlıhemşin Bölgesinde Görülen Tulum Çalgısının Yapısal ve İcrasal Özellikleri" adlı yüksek lisans tezinden üretilmiştir. Çalışmada literatür taraması yapılarak çalgı hakkında elde edilen veriler kronolojik şekilde incelenmiş, alan çalışması yöntemiyle de bölgede çalgının yapımı ve icrası hakkında geniş bilgiye sahip olan kaynak kişiler Varol Taşer ve Murat Atacan'dan alınan veriler sunulmuştur.

Objective: In late December 2019, a cluster of patients with pneumonia caused by an unknown pathogen was reported from Wuhan, Hubei Province, China. The pathogen has been identified as a novel coronavirus, SARS-CoV-2 and the disease has been named as COVID-19. The objective of this study to perform the first holistic scientometric evaluation of coronavirus publications. Methods: Our main source for this study was Web of Science Collection database. All items published between 1980 and 2019 were included. A distribution map of global production in coronavirus literature and scientometric networks were generated. Results: The USA, China, Germany the UK and Netherlands were the most productive countries. Publications in coronavirus literature have been produced from almost every country in the world, except for some countries in Asia and Africa. Conclusion: While in 1980s the USA and developed countries from Europe were major source countries and the virus was identified only as an animal disease in the literature and its biological and genetic structure was investigated, in the 2000s, China became a major contributor of coronavirus literature because the SARS outbreak originated from southern China. Almost all most cited publications in this period are related to SARS and ACE2 protein. In 2010s.