This study aims to evaluate the content and quality of popular videos about blepharoplasty treatment in YouTube. Four keywords “blepharoplasty,” “upper blepharoplasty,” “lower blepharoplasty,” and “blepharoplasty information” were searched in YouTube. After the videos were sorted by the number of views, the last 50 videos were based on general characteristics, primary purpose, information content, relevance, audiovisual quality, as well as viewer interaction index DISCERN score (minimum–maximum: 16–75), Journal of the American Medical Association (JAMA) score (minimum–maximum: 0–4), and Global Quality score (minimum–maximum: 0–5), and view rate formulas were calculated for each video. A total of the best 49 videos were evaluated in our study. The total number of views of these videos was 10,938,976. The total duration of these videos was 409minutes. The average duration of the videos was 8.35±8.38 (standard deviation [SD]). There was no significant (p>0.05) correlation between the measurement of DISCERN scores of the two observers. A significant (p<0.05) difference was observed between the JAMA score measurements of the two observers. There was no significant difference (p>0.05) between the GQS score measurements of the two observers. Currently, YouTube is not a viable resource for patients to learn about blepharoplasty. Physicians should be aware of the limitations and provide up-to-date and peer-reviewed content on the web site, and patients should also be warned about obtaining information.

<b><i>Introduction:</i></b> The aim of this study was to investigate whether N-acetylcysteine (NAC) is effective in the treatment murine model of acute rhinosinusitis in rats. <b><i>Materials and Methods:</i></b> Twelve rats were included in the study. The left nasal cavity of all rats was infected with <i>Streptococcus pneumoniae</i>. Group 1 was the group in which NAC was administered into the left nasal cavity twice daily. Group 2 was selected as the control group. All rats were then sterilely sacrificed under anesthesia after intracardiac blood sampling. After sacrifice, sterile culture samples were collected from the posterior nasal cavity. <b><i>Results:</i></b> Total oxidant status and oxidative stress index (OSI), interleukin 1β, interleukin 6, and tumor necrosis factor α levels decreased significantly in the treatment group. Total antioxidant status was significantly increased. There was a statistically significant increase in total serum thiol levels and native thiol levels. Histopathologic evaluation showed a statistically significant decrease in submucosal gland hypertrophy in the treatment group. <b><i>Conclusion:</i></b> According to our study, intranasal application of NAC can decrease the inflammatory findings in murine acute rhinosinusitis.

Introduction: The purpose of the present study was to determine the possible effect of allergic rhinitis (AR) on voice change in children with acoustic analysis and Turkish children’s voice handicap index-10 (TR-CVHI-10). Methods: This is a case-control study. Forty-one children with AR, and a positive skin prick test, as well as 39 children of controls who had produced a negative skin prick test and lacked a history of allergic disease, were selected for the study. Each assessment included recordings for the purposes of acoustic voice analysis (fundamental frequency [f0], jitter %, shimmer %, and harmonics-to-noise ratio (HNR)), and aerodynamic analysis (maximum phonation time (MPT) and s/z ratio). All participants completed TR-CVHI-10. Results: The mean TR-CVHI-10 score of the AR group was significantly higher than the control group (p = 0.013). No difference was observed between the AR and control groups in terms of jitter, shimmer, HNR, and MPT values and s/z ratio (p > 0.05). Conversely, the f0 value was more pronounced in controls (270.9 ± 60.3 Hz) than in the AR group (237.7 ± 54.3 Hz) (p = 0.012). Conclusion: The study’s results revealed that AR can have an effect on fundamental frequency and voice quality in children. The diagnostic process should include AR as a potential cause of voice disorders in children.