females. Obstet Gynecol 2012;119:772-9.) of a single-dose emergency contraceptive demonstrated young women's ability to appropriately select and correctly use the emergency contraceptive. This post hoc analysis examined the safety of the emergency contraceptive in various age subgroups. METHODS:This was a noncomparative case-series study of a single-dose 1.5 mg levonorgestrel emergency contraceptive. Eligible women were 11-17 years of age and presented to study sites requesting emergency contraception. Safety information (side effects and any medical problems) was collected by telephone or return clinic visit at approximately 1, 4, and 8 weeks after the date the emergency contraceptive was dispensed. Safety data were retrospectively assessed in the following age subgroups: 13-14, 15-16, and 17 years.RESULTS: There were 299 women included in the safety analysis (11-12 year olds, n50; 13 year olds, n52; 14 year olds, n530; 15 year olds, n587; 16 year olds, n5123; 17 year olds, n557). The incidence of treatment-emergent adverse events were 13% (4/32) in 13-14 year olds, 16% (34/210) in 15-16 year olds, and 12% (7/57) in 17 year olds. The emergency contraceptive was well tolerated in all age subgroups. The most commonly reported treatmentemergent adverse event (s) in each age subgroup was as follows: in 13-14 year olds, vaginal bleeding (6% [2/32]); in 15-16 year olds, nausea and headache (each 3% [6/210]); in 17 year olds, nausea and vulvovaginal mycotic infection (each 4% [2/57]).

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Background: Methicillin-resistant Staphylococcus aureus (MRSA) has become more widespread all over the world and it is important to determine methicillin resistance genes in different regions. The major goals of this work were to identify the mec-A gene related with MRSA and to assess the antibiogram of clinical isolates of S. aureus. Methods: Using normal microbiological techniques, 30 clinical Staphylococcal isolates from various specimens were processed to isolate S. aureus. The antibiotic susceptibility test was completed using the Kirby-Bauer disc-diffusion method in accordance with EUCAST criteria. Cefoxitin (30 g) discs were used to screen for MRSA isolates, and the standard polymerase chain reaction (PCR) was used to amplify the mec-A gene. Results: Staphylococcus aureus predominance was 66.6 percent (n = 20) among the 30 bacterial growths. Methicillin-resistant Staphylococcus aureus prevalence was 100% (n = 20), and multidrug resistance was present in 85% (17/20) of the cases (MDR). The majority of the S. aureus isolates were resistant to penicillin (95.2%), cefoxitin (100%), tigecycline (60%) and the combination antibiotics quinipristin-dalfopristin (50%) as well as tobramycin (30) and trimethoprim-methotrexate (20). The results of the PCR show that four out of the twelve isolates analyzed were mecA gene. Conclusion: Without taking antibiotic resistance into account and avoiding antibiotic use, fighting these superbugs won't be achievable. This might quickly escalate into an unmanageable situation. According to this study, MRSA is more common than previously believed and about 80% of isolates are multidrug resistant.