Patients with skin and soft tissue infections may appear with the abscess. Erroneous diagnosis of these entities is common, and should carefully consider the possible alternative diagnoses. Risk for developing skin abscess factors includes disruption of the skin barrier, edema, venous insufficiency, and immune suppression. However, healthy individuals who have no risk factors may also develop these diseases. The most common microbiologic cause of abscess, a commonly group Streptococcus or Streptococcus pyogenes; Staphylococcus aureus (including methicillin-resistant strains) is a notable but less common cause. The most common microbiologic cause of skin abscess is S. aureus; a skin abscess can be caused by more than one pathogen. The diagnosis is based on skin abscess usually on the clinical manifestations. It must be subject to patients with disposable abscess incision and drainage, with a test of culture and susceptibility of materials wet. There is no justification for the blood of patients in the cultures of the abovementioned circumstances. It can be a useful radiographic examination to determine whether the skin abscess is present (via ultrasound) to distinguish cellulitis from osteomyelitis (via magnetic resonance imaging). There may be a justification for radiological assessment in patients with immune suppression, diabetes, venous insufficiency, or lymphedema in patients with persistent symptoms of systemic lymphatic obstruction.