A 77-year-old man with a case of hyperthyroidism with high parathyroid hormone (41 pmol/L), low vitamin D, and normal thyroid-stimulating hormone. The SPECT/CT fused images confirmed the evidence of retrotracheal hyperdense mass approximately 1.0 cm of diameter below the lower pole of the right thyroid lobe with increased uptake, highly suggestive of typical parathyroid adenoma. The most significant point is that there was an incidental finding: high focal uptake in the sellar/suprasellar region corresponding to heterogenous soft tissue lesion suspicious for pituitary adenoma. According to the previous scans, nuclear medicine, CT scan, and the MRI scan indicated pituitary adenoma.

Parkinson's disease (PD) is one of the most common neurological disorder diseases which takes place when brain cells gradually die. PD is considered a challengeable disease because of the similarities between PD and other brain disorders. For this reason, there are several ways to diagnose PD. Nuclear medicine can be a solution to distinguish the similarities between some brain disorders and PD. The aim of this review is to understand the differences between three radiopharmaceuticals used to diagnose PD and to list the advantages and disadvantages of using each radiopharmaceutical. This review includes studies from 2014 to 2019. Every study published before 2014 was excluded. The database used for this search was found in PubMed. English filters and best matches were used to minimize the outcomes. The comparison between PD nuclear medicine agents was established according to three main points: availability and the length of the scan, sensitivity and specificity, and visual evolution. It would appear that using TRODAT 99mTc can be helpful for some departments that other agents cannot offer, especially 123I. However, using MIBG as a biomarker increases the specificity in some studies. MIBG 123I can be used with TRODAT 99mTc as a biomarker. Moreover, applying PET/CT agents can be studied and researched along with nuclear medicine agents. More research studies are needed to understand the relation between cardiac uptake and PD.

A congenital abnormal connection between an accessory spleen and a gonad is called splenogonadal fusion. The parent of a 3-yold boy brought him to King Saud Medical City because he had left scrotal swelling that had begun 1 y previously. 99m Tc-sulfur colloid (SC) imaging has superior sensitivity and specificity in targeting the liver, spleen, and bone marrow, in that these are the only organs that 99m Tc-SC can visualize. Furthermore, if these tissues appear anywhere other than their usual locations, such as in the case of an accessory spleen, 99m Tc-SC imaging can identify them even without biopsy or-in the case of splenogonadal fusion-orchiectomy. In the current case, the patient underwent laparoscopy, the masses were removed, and orchiectomy was avoided. Histopathologic examination confirmed normal splenic tissue, matching the imaging results.