INTRODUCTION:Aloe Vera (AV), is a plant widely used in pharmaceutical, medical, and cosmetic applications. It is known for its therapeutic benefits. The biological active components of AV include antibacterials and antioxidants. Aloe Vera also has anti-inflammatory and immunomodulatory effects which promote tissue regeneration. Aloe Vera gel have been demonstrated as an adjunctive treatment for several inflammatory diseases including periodontitis. OBJECTIVE: To evaluate the effect of AV gel as an adjunctive treatment to SRP in management of chronic periodontitis. MATERIALS AND METHODS:In a randomized, single-blinded study. Patients were divided into two groups, each included fifteen patients with mild to moderate chronic periodontitis having 1-4 mm attachment loss. Group 1 (test): treated with scaling and root planning followed by subgingival application of AV gel at day 1 and after 1 and 2 weeks, and group 2 (control): treated with scaling and root planning only. Probing depth, clinical attachment level and gingival index were measured at baseline and after 3, 6 and 9 months. RESULTS: Compared to baseline, the two groups showed an improvement in all parameters at 9 months follow up. In AV gel group changes from baseline to 9 months were significantly greater compared to control group regarding reduction of PD, GI and CAL gain, moreover, intergroup differences were statistically significant in favor of AV group. CONCLUSION: according to this study results, adjunctive use of AV gel might add advantages to SRP alone in management of chronic periodontitis.

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