Introduction: Inspiratory muscle training (IMT) devices improve respiratory muscle strength, endurance and exercise capacity on healthy subjects. Because of the limited availability of the effect of IMT devices on healthy subjects with minimal activity level, this study was conducted to evaluate the effects of POWERbreath-plus® and Threshold IMT® on healthy subjects by measuring pre and post Maximal inspiratory pressure (MIP), Maximal expiratory pressure (MEP), Peak Expiratory Flow Rate (PEFR) and Mandatory Voluntary Ventilation (MVV) and to compare their effectiveness.