Objective: To determine how combination oral contraceptive pills (COCPs) affect women of reproductive age's lipid profiles, blood pressure, and body mass index. Methodology: This cross-sectional study looked at the family planning programmes at the tertiary referral hospitals in Peshawar. We looked at married, childbearing women (aged 14 to 49). Group 1 (those who had used COCPs for at least six months) and Group 2 (controls of a comparable age who had not used COCPs) were created. Fasting blood TC, TG, HDL-C, LDL-C, and VLDL-C levels were assessed using a chemical analyser. Hb and platelet levels were assessed by a haematology analyst. Everyone had their BMI and blood pressure measured. The parameters of the oral and control groups were compared using SPSS. Results: The average BMI of Group 1 (Oral COCP) was 28.12 kg/m2 (+/- 0.50 SEM), while the average BMI of Group 2 (Control) was 26.25 kg/m2 (+/- 0.43 SEM). The mean BMIs of the two groups were very different (p-value: 0.0003). Women in Group 1 who took combined oral contraceptives had a much higher BMI than women in Group 2 who did not. BMI is used to measure health. It is based on height and weight.

Due to its great prevalence and harmful consequences on health, obesity appears to be a serious problem in today's society. Studies have connected obesity with lower blood calcifediol concentrations. Examining the blood vitamin D levels among overweight and non-obese adults as well as adolescents was the goal of the current study, as well as compare how they responded to the similar oral vitamin D3 treatment. The blood vitamin D levels of a small number of obese children and adults and some obese individuals were compared in a non-randomized clinical study. 1 pearl of vitamin D3 (50 000 Iu) was given to those with a blood vitamin D status of thirty milligrams per milliliter (74 occurrences) every week for six weeks. Two weeks after starting therapy, serum vitamin D levels were tested once again. At baseline, individuals with obesity had a frequency of low Vit D level of 42/44 (95.5%) compared to 31/46 (66.6%) of patients with non- obesity (p 0.002). The aforementioned percentages were reduced to 24/43 (55.8%) and 1/30 (3.3%), respectively, following therapy for these individuals (p 0.001). Our investigation showed that patients, especially those who were obese, frequently had vitamin D deficiencies. Moreover, the obese group shows a modest therapeutic response.