The modulation of several cellular transduction pathways by curcumin has recently been extended to elucidate the molecular basis for obesity and obesity-related metabolic diseases. These findings might enable novel phytochemical treatment strategies as well as curcumin translation to the clinical practice for the treatment and prevention of obesity-related chronic diseases. Furthermore, the relatively low cost of curcumin, safety and proven efficacy make it advisable to include curcumin as part of healthy diet.

Mammalian collagen is a multifactorial biomaterial that is widely used for beneficial purposes in the advanced biomedical technologies. Generally, biomedical applicable collagen is extracted from the mammalian body, but it can also be derived from marine species. Recently, mammalian tissues collagen proteins are considered a great pathological risk for transmitted diseases, because purification of such protein is very challenging and needs efficient tool to avoid structure alteration. Thus, difficult extraction process and high cost decreased mammalian collagen demands for beneficial effects compared to marine collagen. In contrast, marine collagen is safe and easy to extract, however this potential source of collagen is hindered by low denaturing temperature, which is considered a main hurdle in the beneficial effects of marine collagen. Characterization and biomedical applications of marine collagen are in transition state and yet to be discovered. Therefore, an attempt was made to summarize the recent knowledge regarding different aspects of marine collagen applications in the biomedical engineering field.

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