From the black coral Antipathies dichotoma, a sphingolipid (2S*,3S*,4E,8E)-2N-[tetradecanoyl]-4(E),8(E)-icosadiene-1, 3-diol (1) and a steroid (22E)-methylcholesta-5,22-diene-1a,3b,7a-triol (2) were isolated. Other known compounds, 3b,7a-dihydroxy-cholest-5-ene (3) (22E,24S),5a,8a-epidioxy-24-methylcholesta-6,22-dien3b-ol (4) and (22E,24S),5a,8a-epidioxy-24-methylcholesta-6,9(11),22-trien-3b-ol (5). The structures were established on the basis of NMR spectroscopic analysis and comparison with literature. The antibacterial activity of five compounds was evaluated.

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