Obesity does not appear to be an independent factor for allow quality of female sexual life. However, disturbance associated to obesity indicates a low frequency of disorder in physical domains, suggesting that psychological factors seem to be mainly involved in the sexual dysfunction in obese women.
Narcolepsy type 1 is a sleep disorder characterized by excessive daytime
sleepiness (EDS), sleep fragmentation, hypnagogic hallucinations, sleep
paralysis, and cataplexy. Stimulant medications such as modafinil and
amphetamines are the first-line medications for treating sleepiness. However,
the management of narcolepsy during special circumstances of life such as
pregnancy is complex. MMDM is a 34-year-old female with Narcolepsy type 1
treated with modafinil (400mg/d) and citalopram (20mg/d). Before she become
pregnant, modafinil and citalopram were replaced for L-Carnitine 510mg/d with
good outcome. She underwent an usual pregnancy and was submitted to a term
cesarean delivery without child-birth complications. This is the first
description of oral L-Carnitine such an alternative to treatment narcolepsy type
1 during pregnancy. Treat these patients is not easy but care narcolepsy
pregnant is a challenging even bigger. In a disease without many treatment
options, L-Carnitine can be used to treat daytime sleepiness during pregnancy in
narcolepsy.
Purpose. To correlate optical coherence tomography (OCT) measurements with clinical parameters in idiopathic intracranial hypertension (IIH). Methods. A cross-sectional study was conducted with 22 patients with IIH and 11 controls. All participants underwent comprehensive ophthalmological examination followed by spectral-domain OCT (SD-OCT) and standard automated perimetry using the 30–2 program of the Humphrey visual field analyzer. Correlations between ganglion cell complex (GCC) thickness and retinal nerve fiber layer (RNFL) thickness, as measured by SD-OCT, and clinical parameters were assessed using generalized estimating equations. Result. The mean age of the participants was 35.0 ± 10.83 years. The groups were similar regarding age, but were significantly different regarding sex and visual acuity (
p
=
0.001
and
p
=
0.038
, respectively). The GCC was significantly thinner in the IIH group, with a mean of 90.535 ± 9.766 μm compared to 98.119 ± 6.988 μm for the controls (
p
=
0.023
). There was a significant association between GCC thickness and optic disc pallor (
p
=
0.016
) and between edema and visual acuity (
p
=
0.037
). No significant difference was found in RNFL thickness between patients and controls. Conclusion. The GCC was thinner in the patients with IIH compared to the controls, and there was an association between GCC and optic disc pallor. This might suggest a role for OCT parameters when the structural changes that occur in IIH are investigated, possibly guiding clinical decision making.
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