Introduction: Bioceramic-based root canal sealers are novel materials with a bioactivity potential that stands out compared with conventional root canal sealers. However, the term bioactivity may be overused and is often misunderstood. Hence, the objective of this study was to synthesize and map key concepts related to the bioactivity analysis of bioceramic-based root canal sealers. Methods: The present scoping review is reported in accordance with the PRISMA-ScR Statement and is registered in the Open Science Framework. Two blinded reviewers carried out a comprehensive search in six databases up to January 10th, 2022: MEDLINE, Scopus, Embase, Web of Science, Cochrane Library, and Lilacs/BBO. Eligibility was considered for in vitro and in vivo studies that evaluated the bioactivity potential of bioceramic-based root canal sealers. Results: A total of 53 studies were included in the qualitative synthesis. In vitro bioactivity was evaluated through the mineralization potential, formation of carbonated apatite on the surface, and the gene expression related to proteins involved in the mineralization process. Meanwhile, for in vivo studies, staining techniques associated with immunohistochemical tests were mainly used to detect mineralization on the material–host tissue interface. Conclusions: According to the methodology used, the most prevalent methods to assess bioactivity in acellular form were the immersion of the material in Hank’s balanced salt solution, followed by surface observation with scanning electron microscopy and energy dispersive X-ray. In cell cultures, the chosen method was usually Alizarin Red staining, followed by the evaluation of alkaline phosphatase enzymatic activity and the use of molecular biology tests.

O Projeto de Extensão “Anatomia Funcional e Estética para Restaurações Diretas” (AFERD) conta com participação dos professores do núcleo de Dentística da Faculdade de Odontologia da Universidade Federal de Pelotas (UFPel) e está em atividade desde 2018. A fim de manter os alunos engajados em atividades acadêmicas durante o período de pandemia de coronavírus 2 (SARS-CoV-2) em 2020, deu-se continuidade ao projeto de modo remoto. Dessa forma, o objetivo do presente trabalho foi descrever as atividades síncronas e assíncronas desenvolvidas na área de odontologia restauradora em um projeto de extensão durante a pandemia do SARS-CoV-2. O projeto teve duzentos e dez inscritos para a modalidade remota, com uma presença média de cento e vinte três alunos nas atividades síncronas. Foram realizadas dez atividades semanais síncronas com uma hora de duração, juntamente com atividades assíncronas não obrigatórias no Moodle. Para as atividades assíncronas, um total de cento e dezesseis se inscreveram no Moodle, com média de sessenta e três atividades entregues. O projeto conseguiu implementar com sucesso uma estratégia de ensino remoto de odontologia restauradora com um alto número de inscritos e participação ativa de grande parte dos alunos nas atividades assíncronas não obrigatórias. Além disso, foi bem avaliado pelos seus participantes com a maioria pretendendo continuar nele pelo próximo semestre. Dessa forma, o ensino remoto permitiu a continuidade das atividades de dentística para acadêmicos e profissionais da área dentro de um Projeto de Extensão no período de pandemia.

The main cause of unsuccess in endodontically treated teeth (ETT) is due to bacterial recontamination. The placement of an intraorifice barrier (IOB) has been proposed for preventing this event in cases that the restoration is in an inadequate condition, enhancing the possibilities for predictable long-term success in endodontic therapy. Objectives. To evaluate through a systematic review and meta-analysis if it would be necessary to place an IOB in ETT. Materials and Methods. The present review is in accordance with the PRISMA 2020 Statement and is registered in the Open Science Framework. Two blinded reviewers carried out a comprehensive search in four databases up to July 10th, 2021: MEDLINE, Scopus, Embase, and Web of Science. Eligible studies were the ones which evaluated the use of an IOB in ETT in reducing microleakage with any material of choice and with any methods employed. Only in vitro studies published in English were included. Results. A total of thirty in vitro studies were included in the qualitative synthesis, and seven of those were included in the quantitative analyses evaluating the following materials: bioceramic cement, glass-ionomer cement (GIC), and resin-based composite (RBC). Most of the included studies placed an IOB at a 3 mm depth. Reduction in microleakage was observed when an IOB was placed, regardless of the material employed ( p ≤ 0.01 ). Among the materials, GIC and RBC performed similarly ( p > 0.05 ), with the bioceramic subgroup being statistically superior to the GIC subgroup ( p ≤ 0.05 ). Conclusions. Although well-designed randomized clinical trials are required, the placement of an intraorifice barrier can significantly reduce microleakage in endodontically treated teeth, and the use of bioceramics as IOB seems to be the best available material for this purpose.

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