In an urbanized world, the sustainability of cities will depend on their form and urban structure. In this sense, fabrics that are compact, dense, green, and suitable for non-motorized transport methods are more environmentally efficient. For the purpose of contributing new tools to the design, urban planning, and sustainability of nature in residential areas, this study characterizes the urban fabrics of six urban wetlands in the Latin American city of Concepción (Chile), which is known for its blue–green spaces. In a wetland city, we model urban patterns through spatial relationship using a statistical regression model (OLS—ordinary least squares) with the urban variables of density, distance, population, housing, highways, green areas, and building permits. Concepción shows predominantly low- to medium-density fabrics, and it is not integrated with the urban wetlands. In fact, it was observed that the residential areas do not take advantage of the blue–green spaces and that the urban fabrics do not favor proximity, with a transportation network that promotes the use of cars, leading to the wetlands being inaccessible and fragmented. However, as they are still surrounded by open spaces with abundant vegetation, there are highly feasible opportunities for the future development of blue–green infrastructure.

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