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Objective:  Analyze adverse effects of 5–ARI’s regarding sexual health and fertility (erectile dysfunction and decreased libido); neurology and psychiatry (depressive symptoms, self-harm and suicidal ideation); endocrine, metabolic and cardiovascular (increased body fat, LDL and total cholesterol). Bibliographic review: This narrative review reports findings from various scientific articles published online, regarding the adverse effects of 5-ARI`s, often used to treat male-pattern baldness and benign prostate hyperplasia in adult males. Final considerations: Adverse effects were identified on several studies made in different populations. Thus, it is utterly important to raise public awareness of the implications associated with 5-ARI's treatment. Prescription of 5-ARI's therapy should be carefully assessed for each individual due to potential adverse effects that may occur upon its start, and drastically compromise quality of life in adult males.

Os antimicrobianos se apresentam como uma das principais drogas utilizadas nos centros de terapia intensiva (CTIs). Contudo, sua indicação ainda é preocupantemente caracterizada por tratamentos inadequados, apresentando um consequente aumento de bactérias multirresistentes. Nesse contexto, tem-se a antibioticoterapia empírica como importante ferramenta para redução de taxas de mortalidade em quadros de sepse primária. Assim, este estudo objetiva avaliar o perfil de sensibilidade antimicrobiana dos agentes etiológicos de sepse

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