high-velocity solution plasma spray (HVSPS) process. Graded coatings were formed by reactions between the Si(OH) 4 sprayed liquid precursor and the C/C substrate; these reactions were promoted by the high temperature of the plasma torch. The morphologies, microstructures, and chemical compositions of the coatings were investigated by X-ray diffraction, Raman spectroscopy, Fourier-transform infrared spectroscopy, and scanning electron microscopy/energy-dispersive X-ray spectroscopy. By altering the deposition time, the coating thickness was controlled, therefore demonstrating SiC formation and realizing graded SiO 2 /SiC coatings.
In this study, the hybrid corona-dielectric barrier discharge plasma treatment was employed to modify the physical, chemical and morphological characteristics of a half-knitted fabric composed of 92% polyamide 6.6 and 8% elastane (PA). These properties of the fabric were evaluated by the water contact angle, x-ray diffraction, infrared spectroscopy, scanning electron microscopy and atomic force microscopy techniques. In addition, the dyeing and washing processes were also investigated. A significant reduction of the contact angle was observed for plasma-treated PA. Infrared spectroscopy analyses indicated that C-H, N-H, and NO groups in PA increased after plasma treatment, explaining the improved coloring strength for the plasma-treated samples when dyed with reactive and acid dyes. A better fixation of dye was also observed after the atmospheric plasma treatment. Furthermore, dyeing with a basic and acid dye caused the dyeability increases for the plasma-treated sample compared with the untreated sample.
Background
Human papillomavirus (HPV)-related biomarkers such as p16/Ki-67 “dual stain” (DS) cytology have shown promising clinical performance for anal cancer screening. Here, we assessed the performance of automated evaluation of DS cytology to detect anal precancer in men who have sex with men (MSM) living with human immunodeficiency virus (HIV).
Methods
We conducted a cross-sectional analysis of 320 MSM with HIV undergoing anal cancer screening and high-resolution anoscopy (HRA) between 2009-2010. We evaluated the performance of automated DS based on a deep-learning classifier compared to manual DS evaluation to detect anal intraepithelial neoplasia (AIN) grades 2 and 3 (AIN2+) and AIN3. We evaluated different DS-positive cell thresholds quantified by the automated approach and modeled its performance compared to other screening strategies in a hypothetical population of MSM with HIV.
Results
Automated DS had significantly higher specificity (50.9% vs. 42.2%, p=0.0004) and similar sensitivity (93.2% vs. 92.1%) for detection of AIN2+ compared to manual DS cytology. HPV testing with automated DS triage was significantly more specific (56.5% vs. 50.9%, p=0.0003) with the same sensitivity (93.2%) compared to automated DS alone. In a modeled analysis assuming a 20% AIN2+ prevalence, automated DS detected the most precancers compared to manual DS and anal cytology (186,184, and 162, respectively) and had the lowest HRA referral per AIN2+ detected (3.1,3.5, and 3.3, respectively).
Conclusions
Compared to manual evaluation, automated DS cytology detects the same number of precancers with lower HRA referral.
The chemical, structural, morphological, and optical properties of Al-doped TiO2 thin films, called TiO2/Al2O3 nanolaminates, grown by plasma-enhanced atomic layer deposition (PEALD) on p-type Si <100> and commercial SLG glass were discussed. High-quality PEALD TiO2/Al2O3 nanolaminates were produced in the amorphous and crystalline phases. All crystalline nanolaminates have an overabundance of oxygen, while amorphous ones lack oxygen. The superabundance of oxygen on the crystalline film surface was illustrated by a schematic representation that described this phenomenon observed for PEALD TiO2/Al2O3 nanolaminates. The transition from crystalline to amorphous phase increased the surface hardness and the optical gap and decreased the refractive index. Therefore, the doping effect of TiO2 by the insertion of Al2O3 monolayers showed that it is possible to adjust different parameters of the thin-film material and to control, for example, the mobility of the hole-electron pair in the metal-insulator-devices semiconductors, corrosion protection, and optical properties, which are crucial for application in a wide range of technological areas, such as those used to manufacture fluorescence biosensors, photodetectors, and solar cells, among other devices.
In this study, the potential antimicrobial activity of plasma-activated tap water (PAW) was evaluated against Staphylococcus aureus, Escherichia coli, and Candida albicans. For this, PAW was prepared in a gliding arc plasma system using two treatment conditions: stagnant water and water stirring by a magnetic stirrer, called moving water. Subsequently, their oxidation-reduction potential (ORP), pH, electrical conductivity (σ), and total dissolved solids (TDS) were monitored in different areas of the sample divided according to the depth of the beaker. It was observed that PAW obtained in dynamic conditions showed a more uniform acidity among the evaluated areas with pH 3.53 and ORP of 215 mV. Finally, standardized suspensions of Staphylococcus aureus (ATCC 6538), Escherichia coli (ATCC 10799), and Candida albicans (SC 5314) were treated with PAW, and the reduction of viable cells determined the antimicrobial effect. Our results indicate that the tap water, activated by plasma treatment using gliding arc, is an excellent inactivation agent in the case of Staphylococcus aureus and Escherichia coli. On the other hand, no significant antimicrobial activity was achieved for Candida albicans.
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