Background Reports on sex differences in stroke outcome and risk factors are scarce in Latin America. Our objective was to analyze clinical and prognostic differences according to sex among participants in the LASE (Latin American Stroke Registry). Methods and Results Nineteen centers across Central and South America compiled data on demographics, vascular risk factors, clinical stroke description, ancillary tests, and functional outcomes at short‐term follow‐up of patients included from January 2012 to January 2017. For the present study, all these variables were analyzed according to sex at hospital discharge. We included 4788 patients with a median in‐hospital stay of 8 days (interquartile range, 5–8); 2677 were male (median age, 66 years) and 2111 female (median age, 60 years). Ischemic stroke occurred in 4293: 3686 as cerebral infarction (77%) and 607 as transient ischemic attack cases (12.7%); 495 patients (10.3%) corresponded to intracerebral hemorrhage. Poor functional outcome (modified Rankin scale, 3–6) was present in 1662 (34.7%) patients and 38.2% of women ( P <0.001). Mortality was present in 6.8% of the registry, with 7.8% in women compared with 6.0% in men ( P =0.01). Death and poor functional outcome for all‐type stroke showed a higher risk in female patients (hazard ratio, 1.3, P =0.03; and hazard ratio, 1.1, P =0.001, respectively). Conclusions A worse functional outcome and higher mortality rates occurred in women compared with men in the LASE , confirming sex differences issues at short‐term follow‐up.

Despite the limitations of this study, the collected information supports the existence of differences in the clinical and radiological traits of SC patients between Asian and Latin-American hospitals. The possible biological factors that may underlie these differences are discussed.

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Monitoring environmental parameters in urban centers has become a critical step for health risk assessment. In this study, conducted in the industrial park of Mirandela (Portugal), an environmental monitoring system consisting of a meteorological station, a class 1 smart sound sensor and three reference optical gas analyzers were deployed to measure noise levels, tropospheric ozone concentrations, carbon monoxide, and nitrogen oxides, during winter and spring of 2019. The interdependence among all variables was evaluated, and legal compliance was assessed according to the European Union (EU) target values for ozone. Higher concentrations of nitrogen oxides and carbon monoxide were observed during rush hours, while ozone concentrations increased as a consequence of the emissions of primary pollutants after sunrise reaching their maximum values at about 13:00 to 14:00h. Regarding the Accumulated Ozone Exposure (AOT), both target values set by the EU for AOT40 vegetation and forest have been exceeded. For AOT60, the observed values were below target; however, the threshold for NET60 was exceeded even before the end of 2019. Noise levels were higher during rush hours, because of higher traffic intensity; however, noise level indicators (Lden, Ln) remained within the legal limits. It was possible to realize that urban traffic is the most relevant source of noise and local air pollution. These results can be used to define strategies that may improve the environmental performance of the studied industrial park.