Early detection of laryngeal tumors is critical for their successful therapy. In this paper, we investigate how hyperspectral (HS) imaging can contribute to this aim based on an in-vivo data set of 13 HS image cubes recorded in clinical practice. We perform semantic segmentation with a tailored U-Net trained on labels provided by the clinicians. We specifically investigate the influence of exposure time during image acquisition, the suitable wavelengths to determine the most informative image channels, and present quantitative results on accuracy and the AUC measure.* The data set collection was funded by the German Cancer Aid within the project framework "Early detection of laryngeal cancer by means of Hyperspectral Imaging (109825110275)".
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