Evidence-based practice provides the most effective care that is available with the aim of improving clients’ outcome. However, despite existing policies related to encouragement to or requirement of evidence-based practice (EBP), results of reviewed studies show nurses do not generally incorporate research evidence in their daily practice. This study aimed to assess nurses’ attitudes towards knowledge and use of EBP in a teaching hospital in Kuala Lumpur. This study used descriptive cross-sectional survey among 265 nurses (out of 851), working in the different adult medical-surgical wards, who were selected through the quota sampling. Participants in this study, reported positive attitudes towards EBP, good knowledge of EBP, but poor utilization of evidence in their practice. Results of this study affirmed the findings of previous researches, showed despite having positive attitude and perception of good knowledge/skill regarding EBP; nurses did not incorporate evidence into practice. Application of EBP in clinical setting increases the quality of patient care, clients’ outcome and nurses’ job satisfaction and retention. In this regard, nursing managers and authorities have an important role in providing supports, facilities and persuading environment to focus nurses on evidence-based practice. It is recommended that the effect of personal and professional agents on actual EBP activities among nurses should be assessed through the observational studies rather than self-report questionnaire.

Hospital-acquired infections can increase the rate of morbidity and mortality as well as medical costs. Nosocomial infection is spread by various ways such as surgical, intravenous catheters, surface contact (like as hands) and also through the air. Some interventions include appropriate hand and surface decontamination, sufficient staffing, improved ventilator management, usage of coated central venous and urinary catheters have all been linked with considerably lower rate of nosocomial infection. Multiple interventions simultaneously are required for comprehensive infection control and multiple actions may be given better outcome rather than a single action. Some multiple infection control protocols will possibly show more effective result instead of employing a single or few strategies. Several non-pharmacological interventions to prevent HAIs will reduce the requirement for prolonged or multiple-drug antibiotic courses for infected patients. And lower antibiotic usage will decrease risk of antibiotic-resistant organisms and may improve effectiveness of antibiotics therapy to patients with acquired infections.

Background: Hospital-associated infections are related with mortality, extended hospital stay, morbidity and attributable costs to the health care sector. The main objective of this study is measuring infected patients' knowledge on infection control precaution in University Malaya Medical Center. Methods: Survey of 184 infected patients admitted to University Malaya Medical Center (UMMC) in Malaysia determined infected patients' knowledge level regarding infections control activities. Results: Infected patient's knowledge on infection control precaution in given medical center (UMMC) is moderately high with 65.2% good knowledge among infectious patients. Nevertheless, certain knowledge areas of infection control need to improve -i.e., transferring infected patients to isolation room immediately and using facemasks by medical staff while attending patients. The age, level of education of patients and the source of receiving information regarding to controlling infection cannot influence infected patient's knowledge of infection Control. While the gender of patients, patients' job experience in healthcare environment, relatives of patients' job experience in healthcare environment, frequency of hospitals admission and the received information related to controlling infection can influence infected patient's knowledge of infection Control. Conclusions: Actions intended at improving knowledge are essential to the implementation and development of efficient public health preventative strategies.