We aimed to analyze postoperative cognitive dysfunction (POCD) incidence and risk factors in elderly adults who underwent surgery for oral malignancies. A total of 112 elderly patients (aged ≥ 55 years) were selected for extended resection of descending oral malignancies at our institution from December 2020 to December 2021. Participants were cognitively evaluated using the neuropsychological test scale 1 day preoperatively and 7 days postoperatively to determine whether they had developed POCD. Based on whether POCD occurred 7 days postoperatively, patients were classified into the POCD and non-POCD groups. Logistic regression was applied to perioperative factors to analyze the risk factors for POCD onset. Seven days postoperatively, there were 37 (33.1%) POCD morbidities. Multiple factor logistic regression analysis revealed that venerable age (odds ratio [OR]=1.269, 95% confidence interval [CI] 1.056−1.525, P<0.05), low education levels (OR=0.792, 95%CI 0.644−0.974, P<0.05), hypertension (OR=4.153, 95%CI 1.335−12.732, P<0.05), dyssomnia (OR=1.272, 95%CI 1.001−1.617, P<0.05), prolonged anaesthesia (OR=1.009, 95%CI 1.001−1.018, P<0.05), and intraoperative hypotension (OR=5.512, 95%CI 1.240−24.506, P<0.05) increased the POCD risk in elderly patients who underwent surgery for oral malignancies. Venerable age, low knowledge reserve, hypertension, dyssomnia, prolonged anaesthesia, and intraoperative hypotension are independent risk factors for POCD in elderly patients with oral malignancies.

Background: This study aimed to analyse the incidence and risk factors associated with postoperative cognitive dysfunction (POCD) after malignant tumour resection and cervical lymphatic dissection in older adults undergoing oral and maxillofacial surgery. Methods: A total of 112 older patients (aged≥ 55 years) were selected for extended resection of descending oral malignancies at the Affiliated Stomatological Hospital of Chongqing Medical University from December 2020 to December 2021. Participants were cognitively evaluated using the neuropsychological test scale one day preceding and seven days after the surgery to determine whether they had developed POCD. Based on whether POCD occurred after seven days,patients were divided into the POCD and non-POCD groups. Logistic regression was applied to perioperative factors to analyse the risk factors for POCD onset. Results: Seven days following surgery for oral malignancy, there were 37 (33.1%) POCD morbidities. Multiple factor logistic regression analysis revealed that age (OR=1.269, 95%CI 1.056-1.525, P<0.05), low education levels (OR=0.792, 95%CI 0.644-0.974, P<0.05), hypertension (OR=4.153, 95%CI1.335-12.732, P<0.05), dyssomnia (OR=1.272, 95%CI 1.001-1.617, P<0.05), prolonged anaesthesia (OR=1.009, 95%CI 1.001-1.018, P<0.05), and intraoperative hypotension (OR=5.512, 95%CI 1.240-24.506, P<0.05) increased the risk of POCD in older patients who underwent surgery for oral malignancies. Conclusion: Venerable age, low knowledge reserve, hypertension, dyssomnia, prolonged anaesthesia, and intraoperative hypotension are independent risk factors for POCD in older patients with oral malignancies.

We aimed to analyse postoperative cognitive dysfunction (POCD) incidence and risk factors in elderly adults who underwent surgery for oral malignancies. A total of 112 elderly patients (aged ≥ 55 years) were selected for expanded resection of oral malignancy and cervical lymphatic dissection at our institution from December 2020 to December 2021. Participants were cognitively evaluated using the neuropsychological test scale 1 day before and 7 days after surgery to determine whether they had developed POCD. Based on whether POCD occurred 7 days after surgery, patients were classified into the POCD and non-POCD groups. Logistic regression was applied to perioperative factors to analyse the risk factors for POCD onset. Seven days after surgery for oral malignancy, there were 37 (33.1%) POCD morbidities. Multiple factor logistic regression analysis revealed that venerable age (odds ratio [OR] = 1.269, 95% confidence interval [CI] 1.056–1.525, P < 0.05), low education levels (OR = 0.792, 95% CI 0.644–0.974, P < 0.05), hypertension (OR = 4.153, 95% CI 1.335–12.732, P < 0.05), dyssomnia (OR = 1.272, 95% CI 1.001–1.617, P < 0.05), prolonged anaesthesia (OR = 1.009, 95% CI 1.001–1.018, P < 0.05), and intraoperative hypotension (OR = 5.512, 95% CI 1.240–24.506, P < 0.05) increased the POCD risk in elderly patients who underwent surgery for oral malignancies. Venerable age, low knowledge reserve, hypertension, dyssomnia, prolonged anaesthesia, and intraoperative hypotension are independent risk factors for POCD in elderly patients with oral malignancies.