Characterization of porous media is essential in a wide range of biomedical and industrial applications. Microstructural features can be probed non-invasively by diffusion magnetic resonance imaging (dMRI). However, diffusion encoding in conventional dMRI may yield similar signatures for very different microstructures, which represents a significant limitation for disentangling individual microstructural features in heterogeneous materials. To solve this problem, we propose an augmented multidimensional diffusion encoding (MDE) framework, which unlocks a novel encoding dimension to assess time-dependent diffusion specific to structures with different microscopic anisotropies. Our approach relies on spectral analysis of complex but experimentally efficient MDE waveforms. Two independent contrasts to differentiate features such as cell shape and size can be generated directly by signal subtraction from only three types of measurements. Analytical calculations and simulations support our experimental observations. Proof-of-concept experiments were applied on samples with known and distinctly different microstructures. We further demonstrate substantially different contrasts in different tissue types of a post mortem brain. Our simultaneous assessment of restriction size and shape may be instrumental in studies of a wide range of porous materials, enable new insights into the microstructure of biological tissues or be of great value in diagnostics.
We envisage that these materials will be used for the validation of novel and established methods within the field of diffusion MRI, as well as for routine quality assurance purposes and for establishing scanner performance in multicenter trials.
In the textile industry, although there are several methods for obtaining sub-micro-or nanofibres, electrospinning perhaps is the most versatile process. Electrospinning has been recognized as a feasible technique for the fabrication of continuous polymeric nanofibre yarns desired in the textile industry. Various materials including polymers, composites, ceramics and metals have been successfully electrospun into nanofibres in recent years mostly in solution and some in the melt. Potential applications based on electrospun nanofibres as a new-generation material in the textile industry will be realized if suitable nanofibre yarns become available to textile processes like weaving, knitting and embroidery. In this review, we present, from a textile viewpoint, a comprehensive overview of processing technologies of polymeric nanofibres in the textile industry; however, the emphasis here is focused on electrospinning. In particular, we choose to concentrate on a detailed account of research activities on the yarns and fabrics composed of electrospun nanofibres. Our discussion is concluded with some personal perspectives on the future challenges for the development and optimization of yarns based on electrospun nanofibres.
Electrospinning is a well‐established and intensively investigated methodology, and is currently the only known technique that can fabricate continuous nanofibres. The major challenge associated with electrospinning is its production rate, compared with that of conventional fibre spinning. However, the understanding of the scale‐up possibility of the electrospinning process is still in its infancy. Substantial up‐scaling of electrospinning may pave the way for applications of nanofibre assemblies (i.e. yarns) not accessible otherwise in conventional textile processes, such as weaving, knitting and braiding. Here we summarize recent advances regarding the enhancement of electrospinning throughput with special emphasis on multiple jets from multi‐needles and the free surface of polymer solutions. Copyright © 2009 Society of Chemical Industry
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