Better understanding of conditions that predispose MCDK could be a critical step towards improving clinical consequence and management of this disease. Since there is little evidence on the relationship between MCDK and epidemiologic factors, we evaluated this relationship hypothesizing that these epidemiologic conditions would increase the risk of MCDK. Please cite this paper as: Introduction:Multicystic dysplastic kidney (MCDK) is a sporadic developmental abnormality caused by abnormal differentiation of the metanephric that is present as a flank mass in infancy. It may lead to renal dysfunction or death as a result of oligohydramnios or respiratory failure. Objectives: This research had aimed to find a probable related link between the MCDK and epidemiologic factors. Patients and Methods: A total of 120 children were evaluated in this case-control research. The case and control groups included 60 children with MCDK and 60 children without MCDK, respectively. Examinations, interviews and questionnaires carried out by the project and diagnosis by a physician. We analyzed our results data using chi-square and student t test as appropriate. Results: The result of this study did not show significant relationship between epidemiological factors such as age, place of residence for families, sex, family education/occupation/ income, body mass index (BMI), stunted growth, slow growth, good growth, milk intake, water intake, failure to thrive (FTT) and MCDK. Conclusion: This study showed that epidemiological factors do not have a significant effect on the occurrence of MCDK disease.

Conclusions: Montelukast lead to rapid improvement of clinical manifetations in children with pyelonephritis and it can be used as an effective auxiliary treatment in these patients.