Approaching the knowledge of professionals of a multidisciplinary residency program in health contributes to the reflection and analysis of knowledge, with reflexes in the structuring of educational responses aimed at strengthening the effective movement of health promotion in this training modality. This study aimed to understand the knowledge that professionals in a multidisciplinary residency have about health promotion and know the perceptions that they have about the contributions of the residency training process for health promotion practices. This is an exploratory study with qualitative approach, carried out in the context of Integrated Health Residency Program of the School of Public Health of Ceará-ESP-EC, Ceará State, Brazil. Sixteen professionals who had been trained in the program were interviewed. Data from interviews were organized according to content analysis technique and with the support of ATLAS.ti software. Two categories were raised: 1) Health promotion: from information to empowerment; and 2) Multiple training moments: contributions to health promotion practices in Multidisciplinary Residency in Health. The knowledge of residents, inferred from the speeches, sometimes assumed a posture congruent with the theoreticalconceptual international principles of health promotion, strengthening its effectiveness in the country through the Multidisciplinary Residency in Health as a training modality, and sometimes revealed features still related only to the prevention of diseases. Residents demonstrated to be aware of the need to overcome the hegemonic model that considers health professionals as the sole holders of knowledge.