High school is usually a complex academic space due to the adolescent age of the students and the academic demands that are, at each time, a challenge for teachers. Among the main subjects that cause difficulty for the student population is organic chemistry, which is necessary for the comprehensive training of the future bachelor, and which includes basic elements of understanding chemical theories that are related in many ways to daily life. and future work. In this sense, in this work, a ludic proposal has been made for teaching organic chemistry to high school students, considering an experimental group and a control group. The experiment showed that playful games favor learning by 21.91%, achieving more significant teaching in students.