Introdução: O pólipo de prega vocal representa uma lesão benigna comum da laringe e o seu tratamento tem diversas modalidades. O objetivo deste artigo é apresentar aspectos clínicos e cirúrgicos específicos destes pólipos. Forma de estudo: Clínico retrospectivo. Material e Método: Levantamento retrospectivo de todos os casos atendidos no ambulatório de laringe da Faculdade de Medicina do ABC durante 18 meses e análise completa de todos os dados obtidos. Discutimos ainda as possibilidades terapêuticas e os resultados relatados na literatura. Resultados: Foram atendidos 108 pacientes no período acima e o diagnóstico mais prevalente foi pólipo de prega vocal (29,62%; n = 32), sem predileção por sexo. O principal sintoma referido foi disfonia (100%) e em 56,25% o tabagismo estava presente, seguido de abuso vocal (25%). Vinte seis pacientes (81,25%) foram tratados por microcirurgia de laringe com laringoscópio de suspensão sob anestesia geral e fonoterapia pós-cirúrgica, além de higiene vocal e tratamento medicamentoso quando necessário. Em 95% destes houve melhora da qualidade vocal após 60 dias de pós-operatório. Conclusões: O tratamento cirúrgico do pólipo de prega vocal apresenta diversas modalidades, porém o sucesso terapêutico depende da habilidade técnica do cirurgião, dos cuidados pós-operatórios e seguimento completo fonoterápico e medicamentoso.
destas apresentaram flora mista. Os microorganismos mais prevalentes dentre os aeróbicos foi o Streptococcus viridans (41,5%) e, dentre os anaeróbios, Peptostreptococcus micros e Peptostreptococcus sp (5,7% e 3,8%, respectivamente). A associação entre penicilina cristalina e metronidazol foi o tratamento preconizado em 31 pacientes (54,3%). Nos demais, diversos antibióticos como clindamicina, cefalosporinas de terceira geração, cloranfenicol e oxacilina foram utilizados. Cinqüenta e quatro pacientes (94,7%) evoluíram satisfatoriamente, dois (3,5%) apresentaram deiscência da ferida cirúrgica e um (1,7%) foi a óbito por mediastinite. Conclusão: os abscessos cervicais ainda configuram uma importante causa de morbidade em nossa população e suas complicações requerem vigilância para a prevenção e abordagem oportunas, especialmente pelo tratamento mais adequado.
OBJECTIVE: The purpose is to evaluate the effectiveness and safety of intranasal cinnamon extract (CE) in the management of patients with allergic rhinitis (AR). METHODS: This is a systematic review, using the standard methodological procedures recommended by Cochrane to search six databases: Cochrane, PUBMED, EMBASE and LILACS, from database inception up to May 2020, to identify randomized controlled trials evaluating the use of CE in treatment for AR. RESULTS: We included two trials involving a total of 100 participants. The studies were at low risk of bias. All studies had similar participant selection criteria and outcome measurement, enabling a meta-analysis. Both studies used a validated instrument (Rhinoconjunctivitis quality of life questionnaire – RQLQ) for this primary outcome (SMD -1.06; 95% confidence interval (CI) -1.58 to -0.59, P <0.0001). . All studies resulted in at least some clinical benefit with the use of CE compared to placebo. None of the included studies reported any significant adverse effects. CONCLUSION: Despite the evidence from two studies showed certain positive effects of response for CE under evaluation in treatment of AR. We found no evidence regarding the effectiveness of cinnamon bark extract for allergic rhinitis. Well-conducted randomized clinical trials using CE are needed to further advance our understanding of the effectiveness of AR.
OBJECTIVE: To evaluate the efficacy and safety of Venlafaxine for the control of vestibular migraine (VM). METHODS: This is a systematic review of randomized clinical trials. The following databases were searched: PUBMED (1966-2021), EMBASE (1974-2021) and CENTRAL (Cochrane Library-2021). There was no geographic and period limitation in the survey. Data extraction and study quality assessment were carried out by two independent researchers. RESULTS: The search strategy identified 47 studies, of which 2 were included in this review, as they met the inclusion and exclusion criteria. Both evaluated the efficacy of venlafaxine in vestibular migraine, comparing the results with other drugs. The first study (2017) compared the effect of venlafaxine with flunarizine and valproic acid, while the second study (2015) compared the efficacy of venlafaxine with propranolol. Both showed improvement of vestibular symptoms in all groups evaluated, but only the groups submitted to treatment with venlafaxine showed a significant change in the emotional DHI (Dizziness Handicap Inventory) score and improvement in depressive symptoms. CONCLUSIONS: Although venlafaxine appears to have promising results, there is currently a scarcity of studies that allow currently to assess the efficacy and safety of the drug for the treatment of vestibular migraine. The evidence is quite limited, the number of studies and patients evaluated reduced, and it is recommended to conduct new quality randomized clinical trials to elucidate the issue.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.