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Objectives This study aims to evaluate whether there was a difference between oxidative stress index (OSI), total antioxidant status (TAS), and total oxidant status (TOS) values between patients with fibromyalgia syndrome (FMS) and healthy controls, and to show the effect of balneotherapy on clinical conditions such as pain, depression, and quality of life in patients with FMS and oxidative stress. Patients and methods Thirty-five females (mean age 39.9±5.8 years; range, 18 to 50 years) with fibromyalgia and 35 healthy females (mean age 37.9±6.6 years; range, 18 to 50 years) were included in the study. The TAS, TOS, and OSI of patients with FMS and healthy controls were measured. Disease severity was evaluated using the Fibromyalgia Impact Questionnaire, pain levels were evaluated using a visual analog scale (VAS), mood was evaluated using the Beck Depression Inventory (BDI), and quality of life was evaluated using the Short Form 36 (SF-36). Patients with FMS were given 15 sessions of balneotherapy. After treatment, the laboratory and clinical parameters of the patients were reevaluated. Results Although the TAS levels of patients with FMS were not significantly different from those of the control group (p=0.114), the TOS and OSI levels were higher than those of the control group (p<0.001). The VAS, BDI, and SF-36 parameter scores of patients with FMS were significantly higher than those of the control group (p<0.001). A statistically significant decrease (p<0.001) in TOS and OSI levels of patients with FMS was detected after balneotherapy; however, the TAS levels of patients with FMS did not change significantly (p=0.538). All clinical parameters showed significant improvement with balneotherapy (p<0.001). Conclusion An oxidative disorder was detected in patients with FMS compared with the control group. Balneotherapy showed antioxidant activity and decreased oxidative stress while also improving clinical parameters and quality of life.

ÖZETPsöriatik artrit, psöriazisli hastaların yaklaşık %14-30'unda görülebilen inflamatuvar bir artrit çeşididir. Bu inflamasyon, vasküler hasara yol açarak serebrovasküler hastalık ile sonuçlanabilir. Bu makalede psöriatik artritli, karotid arter trombozu ile prezente olan 40 yaşındaki bir erkek olgu sunulmuştur. ABSTRACTPsoriatic arthritis is an inflammatory arthritis that can be observed in %14-30 of patients with psoriasis. So that this inflammation could also be responsible for vascular damage which could end up with cerebrovascular diseases. We report a 40 year-old patient with carotid artery thrombosis who had been diagnosed with psoriatic arthritis..