Obesity is an increasing weight that exceeds the limits of physical and skeletal needs due to the excessive backfilling of body fat. Obesity is a predisposing factor for increasing triglyceride levels (TG) and insulin resistance status. Consumption of fiber, such as Tempeh Gembus can be an alternative treatment to lower TG levels and insulin resistance status. This research was aimed to prove the influence of processed Tempeh Gembus to TG levels and insulin resistance status. This research employed a pre-post randomized control group. The participants of this research are 40 women with pre-menopausal obesity which are divided into two groups: the control group which is given the daily standard diet treatment Isocaloric 30 kcal/kg of BW/day and the treatment group which is given the daily standard diet Isocaloric 30 kcal/kg of BW/day with the addition of processed Tempeh Gembus processed as much as 150 g/day for 28 days. The result show, giving Tempeh Gembus to the treatment group can lower the TG level (p = 0.010) and insulin resistance status (p = 0.000) significantly. The decreased levels of TG in the treatment group (-9.3±9.6 mg/dL) were higher compared to the decline in the control group (-2.90±4.43 mg/dL). Decreased insulin resistance status in the control group (- 0.60±0.51) is lower than the treatment group (-6.90±4.82). Based on the results above, consumption of 150 g/day of processed Tempeh Gembus for 28 days can lower TG levels

Obesity causes chronic inflammatory reaction is characterized by elevated levels of high sensitivity c-reactive protein (hscrp). Hscrp and hdl could be used as an early marker of cardiovascular disease risk. Tempeh gembus contain fiber, unsaturated fatty acids and antioxidants, which can reduce the inflammatory reaction. This study determines the effect of processed Tempeh gembus on hsCRP and HDL in obese women. This study included in experimental studies with randomized post-test only control group design involving 40 obese women aged 20 – 50 years. Subjects were randomized into two groups: a control group was given a standard diet low in calories 30 calories/kg body weight, and the treatment group was given a standard diet low in calories 30 calories/kg body weight and Tempeh gembus for 28 days. hsCRP and HDL levels were measured before and after the intervention, food intake was measured by using a 3 x 24-hour recall and physical activity (IPAQ form). HsCRP levels were measured using the ELISA method, whereas HDL levels were measured using the CHOD-PAP method. Wilcoxon test (hsCRP levels) and paired t-test (HDL levels) used to test differeces before and after intervention each group. Mann Whitney test (hsCRP levels) and independent sample test (HDL levels) used to test differeces before and after intervention between groups. There are differences in hsCRP levels before and after the intervention in the control group (p = 0.00) and the treatment group (p = 0.00). There are differences in HDL levels before and after the intervention in the control group (p = 0.00) and the treatment group (p = 0.00). There are differences in the decrease hsCRP levels between the two groups (p = 0.00). There are differences in the increase in HDL levels between the two groups (p = 0.03). Tempeh gembus 150 grams/day can decrease hsCRP levels and increase HDL levels in women with obesity.

Penelitian ini bertujuan untuk mengetahui pengaruh pembatasan makanan terhadap kadar trigliserida dan status resistensi insulin pada wanita obesitas pre-menopause dengan menggambarkan karakteristik responden berdasarkan usia dan aktivitas fisik. Rancangan penelitian pre-post randomized control group design pada 20 orang wanita obesitas pre-menopause yang diberikan perlakuan pembatasan asupan makan isokalori 30 kkal/kgBB/hari. Uji Indeks Massa Tubuh atau IMT, asupan makan, kadar trigliserida dan status resistensi insulin sebelum dan sesudah perlakuan dilakukan dengan menggunakan uji paired samples test. Hasil penelitian menunjukkan bahwa terdapat perbedaan signifikan terhadap IMT; asupan energi; asupan protein; asupan lemak; kadar trigliserida, dan status resistensi insulin namun tidak terdapat perbedaan signifikan terhadap asupan karbohidrat sebelum dan sesudah perlakuan. Kesimpulannya, pembatasan asupan berpengaruh terhadap penurunan kadar trigliserida dan status resistensi insulin.Restriction effect on Eating Intake of Pre-Menopausal Obese Women against Triglyceride Levels dan Insulin Resistance StatusAbstractThis study aims to determine the influence of food restriction on triglyceride levels and insulin resistance status in pre-menopause obese women by describing the characteristics of respondents based on age and physical activity. Pre-post randomized control group design was used as experimental study using 20 pre-menopause obese women. The participants received the restriction of their intake as 30 kcal/kgW/day. The Body Mass Index or BMI, food intake, triglyceride levels and insulin resistance were tested before dan after the treatment using test paired samples test. The results showed that there was significant differences on BMI; energy intake; protein intake; fat intake; triglyceride levels, dan insulin-resistance status but there was no significant difference on carbohydrate intake at before and after treatment. The study concluded that intake restriction resulted in the decrement of triglyceride levels and insulin resistance status.