A case of histiocytic necrotizing lymphadenitis involving a right submandibular lymph node is described in a 14-year-old Caucasian boy. The diagnosis was established on initial assessment by fine needle aspiration biopsy. Excisional biopsy, performed because the lymph node enlargement failed to regress, confirmed the cytological findings.

Two cases of hyalinizing trabecular adenoma of the thyroid are presented. The diagnosis was established on initial assessment by fine-needle aspiration biopsy. Histologic evaluation of the surgical specimens confirmed the diagnosis of hyalinizing trabecular adenoma.

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A case of Kimura’s disease involving two intraparotid lymph nodes is described in a 16-year-old Caucasian boy presenting with a painless swelling of the right parotid gland. A preoperative diagnosis of Kimura’s disease was made on the basis of fine-needle aspiration biopsy (FNAB) and was confirmed by histological evaluation of the surgical specimen. FNAB is a safe and accurate procedure that can be used in the outpatient setting to enable a prompt preliminary diagnosis.

Highlights There are several entities that can cause a head and neck expansive bone lesion and it’s important to consider a neoplastic cause. This report presents the case of a patient with a central dentinogenic ghost cell tumor. The patient underwent an extensive local resection and 10 months after surgery there are no signs of local recurrence. Due to its rarity, increased clinical awareness about this entity is essential to optimize the approach of these patients.