The nosocomial infection could be acquired through airborne disease in the hospital. However, only a particular health center in Indonesia carried out a complete, cautious prevention procedure by utilizing air purifiers due to cost problems. Thus, to minimize the number of nosocomial infections related to bacterial air pollutants, excellent tools with low cost are required to address this problem. We developed an ultraviolet light system within the air purifier at a low cost and the best way to eradicate pathogenic microorganisms in the healthcare center. The study was conducted at the Faculty of Medicine, Universitas Padjadjaran, Bandung in 2009–2010. The room prototype was built from a transparent glass material with two holes at the upper corner as an inlet and outlet pipeline canal. In the middle of the pipeline circulation, a vacuum pump, ultraviolet system, and a cooler were installed so the air will initially flow through those devices before being re-circulated into the room through the pipeline's inlet hole. A fan was set on the room floor, and several ten-centimeter apart, Petri dishes containing microbial growth medium were placed. The microbial colonies from the room with and without the installed ultraviolet system in the air purifier were then compared for analysis. The result showed that an air purifier equipped with an ultraviolet system killed microorganisms 73% more effective than the air purifier without an ultraviolet system (p<0.05). In conclusion, employing an ultraviolet system within the air purifier might be effectively killed microorganisms and ultimately reduce nosocomial infection. PENGEMBANGAN AIR PURIFIER RUANGAN DENGAN PEMANFAATAN SINAR ULTRAVIOLET UNTUK MEMBUNUH MIKROB BAWAAN UDARAInfeksi nosokomial dapat ditularkan melalui penyakit yang ditularkan melalui udara di rumah sakit. Namun, hanya rumah sakit atau pelayanan kesehatan tertentu di Indonesia yang melakukan prosedur pencegahan infeksi nosokomial secara optimal dengan memanfaatkan air purifier karena kendala biaya. Oleh sebab itu, untuk meminimalkan jumlah infeksi nosokomial yang terkait dengan bakteri pencemar udara diperlukan pengembangan air purifier yang baik dengan biaya yang murah. Kami telah mengembangkan sistem pembersih udara yang terintegrasi sinar ultraviolet dengan biaya rendah untuk mengurangi mikroorganisme patogen di ruang pelayanan kesehatan. Penelitian dilaksanakan di Fakultas Kedokteran, Universitas Padjadjaran, Bandung pada tahun 2009–2010. Prototipe ruangan dibuat dari bahan kaca transparan dengan dua lubang di sudut atas sebagai ruang instalasi pipa saluran masuk dan keluar. Pada bagian tengah sirkulasi pipa dipasang pompa vakum, sistem ultraviolet, dan pendingin sehingga udara akan mengalir melewati alat-alat tersebut sebelum disirkulasikan kembali ke dalam ruangan melalui lubang masuk pipa. Sebuah kipas dipasang pada prototipe ruangan dan setiap jarak sepuluh sentimeter ditempatkan cawan Petri yang berisi media pertumbuhan mikrob. Koloni mikrob dari ruangan model dengan dan tanpa sistem ultraviolet yang terpasang di air purifier kemudian dibandingkan untuk dianalisis. Hasil penelitian menunjukkan bahwa air purifier yang dilengkapi sistem ultraviolet membunuh mikroorganisme 73% lebih efektif daripada air purifier tanpa sistem ultraviolet (p<0,05). Simpulan, penggunaan sistem ultraviolet dalam air purifier efektif membunuh mikroorganisme dan pada akhirnya dapat mengurangi infeksi nosokomial.

Background: Asthma, eczema and allergic rhinitis are influenced by both genetic factor and environtment factors. Based on family history of allergy, allergic trace cards can identify the level of allergic risk in children. The relationship between family history of allergy and manifestation of allergic disease as a single allergy disease and allergic multimorbidity still need to be explored. The objective of this study was to identify the associations between family history of allergic disease and manifestation of allergic disease in school-age children.Methods: We conducted a cross sectional study on school age children with 6-13 years old at eight elementary schools in Yogyakarta. Family history of allergy was defined as reported asthma, eczema and allergic rhinitis in a parent or sibling and classified the level of allergic risk based on allergic trace cards. Subjects were questioned by standardized ISAAC questionnaire. The relationship between the two was analyzed by the Chi-squared analysis to assess the prevalence ratio (PR).Results: A total of 272 children with an average age of 8.4 years, allergic manifestations occurred more as multimorbidity (53%) with the highest incidence of RA+asthma (9%) compared with one allergic disease (47%) with the highest incidence of RA (11%). There was a significant relationship between family history of allergy and all manifestations of allergic disease with an increased risk of developing allergies by 3.3 (PR 3.3; 95% CI 2.3-4.8) and 2.8 times (PR 2.8; IK95% 1.8-4.3) in the moderate and high-risk score group. Asthma, RA and DA have a risk for coexistence with 2 other diseases of 2.5 (RP 2.5 IK95%; 1.9-3), 2.25 (PR 2.25 IK95%; 1.7 -3) and 1.9 times (PR 2.5 IK95%; 1.45-2.4).Conclusion: Family history of allergic disease is a risk factors for the development of allergic manifestation both a single allergic disease and multimobidity.