Diabetes Mellitus (DM) is not only a metabolism disorder, but it is a real pandemic disease that interests all continents in this last decade. According to estimates of the International Diabetes Federation (IDF), 379 million people suffer from diabetes in the world in 2014 and 77% of them lived in low and middle income countries, but this number will increase to 205 million in 2035 [1]. For Center of Disease Control and prevention (CDC) in the United States 29.1 million people (9.3% of population) having diabetes in 2012, 27.8% of them are undiagnosed and it interests overall people of 65 years old or older, but the number of young diabetic people has increased in last years [2].