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Multivariate analysis techniques could be used to identify possible intercorrelations in intoxications cases. The statistical analyses used were a multiple logistic regression, multiple correspondence analysis, principal component and hierarchical cluster analysis. Of the 320 samples analysed, 192 samples were positive for some of the investigated toxic agents, of which 100 were positive for ethanol and 131 were positive for other substances. It was possible to group the patients into 3 clusters, which appears 66.5% of this information in the three first factorial axes. On the first axis, the male patients were separated from the female patients. Patients exposed to drugs, between 30 and 39 years old were grouped in the same cluster. On the second factorial axis, patients who were intoxicated with ethanol and who became intoxicated with diazepam were grouped. This work contributed to the mapping of intoxication cases at the Poison Control Centre of the São Paulo city, Brazil (CCI-SP) and serves as an initial study for the creation of a database that could be updated constantly and thus could provide a toxicovigilance system for educational policies.

The chemical composition of the essential oil, phenolic contents, and foliar nutrients of Eucalyptus microcorys leaves, cultivated in Brazil, was analysed on a monthly basis for one year. Canonical redundancy analysis correlated results with climate conditions (rainfall, humidity, and mean temperature), allowing three groups to be distinguished as regards temperature, flavonoids, and the content of some metals. Strong correlations between Mn, Cu, Zn, Ca, P, and K with some monoterpenes and phenolic compounds were observed. Oxygenated monoterpenes were predominant in all sampling months. Oil chemovariation may be influenced by climatic factors as well as by foliar nutrient variation.

Exogenous poisonings are one of the principal accidents involving children and adolescents. The social isolation promoted by the COVID-19 pandemic raises concerns about the possibility of an increase in poisoning among children since most cases of poisoning occur in home environments. Therefore, the present study evaluated exogenous poisonings in children under ten years of age and adolescents aged 11 to 20 years old through data recorded at the Toxicological Information and Assistance Center in the Federal District (CIATOX-DF) from January to September 2020. The results showed a change in the number of notifications, with 1.037 poisonings registered in patients under 20 years of age. Registrations of poisoning by venomous animals, medications, and household cleaning products in children tend to be higher in months of vacation. This study demonstrated poisoning notifications by non-venomous animals in March and April and household cleaning products as the second leading cause of exogenous poisoning, demonstrating a clear temporal association among social isolation, increased use of household cleaning products, and exposure to these products. The multivariate analysis methodology managed to show the significant characteristics of the studied sample, contributing to creating local actions that aim to reduce the number of preventable cases of poisonings.