Purpose-Magnetic fluid hyperthermia experiment requires a uniform magnetic field in order to control the heating rate of a magnetic nanoparticle fluid for laboratory tests. The automated optimal design of a real-life device able to generate a uniform magnetic field suitable to heat cells in a Petri dish is presented. The paper aims to discuss these issues. Design/methodology/approach-The inductor for tests has been designed using finite element analysis and evolutionary computing coupled to design of experiments technique in order to take into account sensitivity of solutions. Findings-The geometry of the inductor has been designed and a laboratory prototype has been built. Results of preliminary tests, using a previously synthesized and characterized magneto fluid, are presented. Originality/value-Design of experiment approach combined with evolutionary computing has been used to compute the solution sensitivity and approximate a 3D Pareto front. The designed inductor has been tested in an experimental set-up
4 0 -Nonafluorobutylstyrene (3) was synthesized and polymerized by conventional and controlled radical polymerization (iodine transfer polymerization (ITP)). Such an aromatic fluoromonomer was prepared from Ullmann coupling between 1-iodoperfluorobutane and 4-bromoacetophenone followed by a reduction and a dehydration in 50% overall yield. Two radical polymerizations of (3) were initiated by AIBN either under conventional or controlled conditions, with 1-iodoperfluorohexane in 84% monomer conversion and in 50% yield. ITP of (3)
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