Aims To determine whether DTPP+Hib vaccination (diphtheria, tetanus, pertussis, poliomyelitis +/x haemophilus) increased the risk of sudden unexpected death (SUD) in children under 3 months of age. Methods We conducted a multicentre case-control study in the 28 French`SIDS Centers'. Case selection was based on death labelled sudden infant death syndrome (SIDS) of an infant aged between 30 and 90 days. Three living controls were selected, matched for sex, gestational age and born immediately after the victim in the same maternity unit. Conclusions DTPPtHib immunization is not a risk factor for early SUD. In this population, we found the same risk factors as described for SIDS.

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