Background:The selenium-binding site in selenium-binding protein (SBP) homologues was not identified.
Results:The Arabidopsis thaliana SBP1 selenium-binding site was characterized as a R-S-Se(II)-S-R-type complex involving Cys 21 and Cys 22 . Conclusion: This is the first identification of the selenium-binding site in any SBP. Significance: It is an important step toward a better understanding of the link between selenium binding and function of SBP.
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