No abstract

Background Low carbohydrate diet (LCD) can improve inflammation and obesity and also circadian rhythm disorders can lead to increased inflammation in obese individuals. The purpose of this study is to evaluate the association between adherence of LCD and circadian rhythm mediated by inflammatory markers including transforming growth factor-β (TGF-β), interleukin-1β (IL-1β) and Galectin-3 in overweight and obese women. Methods 304 women affected by overweight and obesity were enrolled. We evaluated LCD scores by Semi-quantitative food frequency questionnaire (FFQ) of 147 items. The morning-evening questionnaire (MEQ) was applied to evaluate the circadian rhythm. Biochemical parameters such as inflammatory markers and anthropometric components were assessed. Results There was a negative significant correlation between adherence of LCD and circadian rhythm status. In other words, as the LCD scores increased, the odds of circadian rhythm disturbance in intermediate group and morning type persons decreased compared to evening type. It was showed that, IL-1β and Galectin-3 in intermediate and morning type groups, destroyed the significance of this relationship and may be considered as mediating markers. Conclusion Adherence of LCD can improve the circadian rhythm by reducing levels of inflammatory markers and may be considered as a treatment for obesity.

In the family scrapbook compiled by Gesina ter Borch (1633-1690), there is a remarkable drawing of an Iranian youth. Art-historical and scientific research has revealed that although the drawing has areas of later overpainting, there is an original Safavid miniature from the sixteen-fifties or sixties underneath them. It is likely that Gesina herself was responsible for these overpaints, when she mounted the badly damaged miniature in her album at some time between 1660 and 1680. Interestingly, aside from the blackened background and the colourful feather and sashes she added, she attempted to follow the original Iranian style in her restorations. The original was made in the sixteen-fifties or sixties by a painter of the Isfahan School, who probably took his inspiration from an older composition by the famous court artist, Riza Abbasi. The article goes on to show that Riza Abbasi’s work was known in the Dutch Republic before then. In 1623 the junior merchant Niclaes Hem travelled to Iran. He was a member of a Dutch East India Company delegation seeking to negotiate a trade agreement with the Shah. Hem acquired a series of drawings by or after Riza Abbasi while he was in Isfahan. He was probably helped in this acquisition by his fellow countryman, Jan van Hasselt. A number of the original miniatures that Hem took back to the Republic were published as woodcuts in Johannes de Laet’s Persia (1634).

In February 1617, Jan Lucasz. van Hasselt arrived in Persia accompanying Pietro Della Valle (1586–1652), a Roman noble. Sometime between 1618 and 1621 Van Hasselt entered the service of Shah ʿAbbas I (r. 1588–1629), for whom he worked as a painter until the death of the shah. Later, during the reign of Shah Safi I (r. 1629–42) and until 1654 he tried to establish himself as a commercial agent for Persia. The present paper examines the career of this Dutch painter in Persia and the Netherlands. Meanwhile the artworks that may be attributed to him will be discussed.