Anorexia nervosa (AN) is a complex mental health disorder that may result in life threatening medical complications if not properly treated. Refeeding and weight restoration are the primary goals of treatment in AN. A multidisciplinary team is essential during this process in order to properly monitor and address complications that can arise during refeeding. There are benefits and drawbacks to different approaches to refeeding and weight restoration, however, recent research supports more aggressive approaches to refeeding and weight restoration. This review explores recommendations for methods of refeeding from various professional organizations, current standards of practice, as well as management of complications that may arise during the refeeding process. Abbreviations and symbols IntroductionThe Diagnostic and Statistical Manual of Mental Disorders, 5 th Edition defines anorexia nervosa (AN) as the restriction of energy intake relative to requirements leading to significantly low body weight, in conjunction with an extreme fear of gaining weight and a distorted view of body weight and shape [1]. AN is defined as either restricting type (AN-R) or binge-eating/purging type (AN-BP). AN-R occurs "when weight loss is accomplished primarily through dieting, fasting and/or excessive exercise". AN-BP is diagnosed "when during the last three months the individual has engaged in recurrent episodes of binge eating or purging behavior (i.e., self-induced vomiting or misuse of laxatives, diuretics, or enemas)" The severity of AN is defined by body mass index (BMI): mild: BMI > 17 kg/m 2 , moderate: BMI 16-16.99 kg/ m 2 , severe: BMI 15-15.99 kg/m 2 , and extreme: BMI <15 kg/m 2 .The overall prevalence of AN is estimated to be 1-2% of females between the ages of 15-35. Males have a rate of 0.1% and the overall female to male ratio is 1:20 [2][3][4]. AN has the highest mortality rate of any psychiatric disorder, with a reported mortality rate of 5.6% [5]. Medical complications related to the disorder result in 50% of the deaths in individuals with AN, and at least half of the remainder of the deaths have resulted from suicide. The peak occurrence of AN is during adolescence and early adulthood. Longitudinal studies have identified body dissatisfaction, dieting and picky eating as possible predictors for eating disorders. Additionally, multivariate studies have found obsessive-compulsive personality disorder as well as generalized anxiety indicate to have a strong predictive value for AN [3].
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