Ultrasonography may be helpful in diagnosing giant-cell arteritis, but cautious interpretation of the test results based on clinical presentation and pretest probability of the disease is imperative.
STEOPOROSIS IS A COMMONdisease characterized by reduced bone mass and an increased risk of fracture, which affects up to 30% of women and 12% of men at some point during life. Bone mineral density (BMD) is an important clinical predictor of fracture risk, and most of the variance in BMD is genetically determined. 1,2 Many other predictors of fragility fracture are also under genetic control, however, including ultrasound properties of bone, biochemical markers of bone turnover, and skeletal geometry. A wide variety of candidate genes have been investigated in relation to osteoporosis outcomes, but one of the most widely studied is the
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