Introduction: To assess the efficacy and evidence-based data in the literature about rehabilitation therapy in patients with post-prostatectomy urinary incontinence. Materials and Methods: An analysis of published full-length papers identified by a Medline search from 1990 through 2004 was carried out. Abstracts published in peer-reviewed journals in the same period of time were also considered. Results: Efficacy, tolerability and safety of rehabilitation therapy were evaluated, according to the available data in the literature, with special regard to randomized controlled trials in order to define a clear-cut, evidence-based efficacy of this form of therapy. Conclusions: Rehabilitation therapy is a simple and safe way of managing post-prostatectomy urinary incontinence. Nonetheless, few randomized controlled studies have been carried out so far to establish its evidence-based efficacy and it is thus not possible to be scientifically sure of its value. It is therefore necessary to undertake well-designed randomized controlled studies, with a large number of patients, a well-matched control group and an adequate follow-up.

In conclusion, our study, even if supported by preliminary results, showed how Diallyl Thiosulfinate, Nuciferine and Diosgenin is able to improve the control of ejaculation in patients suffering from PE, primary or secondary to ED without any significant adverse effects.

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Urinary incontinence rates after radical retropubic prostatectomy vary widely among the different series and depending on the different scoring systems, from 2–10% up to 87%. Rehabilitation therapy is the safest and simplest treatment available so far, although a wide consensus on the efficacy of its results is still lacking. In our experience, treating post radical prostatectomy incontinent patients with rehabilitation therapy has been safe, reproducible and without side effects; nevertheless, our results suggest its use only in mild to moderate cases of post radical prostatectomy urinary incontinence.