SummaryWe tested 70 blood donors from Fortaleza (Ceara state, Brazil) for GB virus C/hepatitis G virus (GBV/HGV) infection by polymerase chain reaction and detection of antienvelope antibodies. Twenty-seven (38.6%) showed signs of an active or resolved infection. Sixty-four percent of those with indications of other bloodborne viral infections showed signs of GBV-C/HGV infection also.keywords GBV-C, HGV, Brazil, Fortaleza, transfusion, blood-borne viruses correspondence Prof.