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Objective: Although several COVID-19 vaccines are available, the current challenge is achieving high vaccine uptake. We aimed to explore university students’ intention to get vaccinated and select the most relevant determinants/beliefs to facilitate informed decision-making around COVID-19 vaccine uptake.Methods: A cross-sectional online survey with students (N = 434) from Maastricht University was conducted in March 2021. The most relevant determinants/beliefs of students’ COVID-19 vaccine intention (i.e., determinants linked to vaccination intention, and with enough potential for change) were visualized using CIBER plots. Results: Students’ intention to get the COVID-19 vaccine is high (80 %). Concerns about safety and side effects of the vaccine and trust in government, quality control, and the pharmaceutical industry are identified as the most relevant determinants of vaccine intention. Other predictors are risk perception, attitude, perceived norm, and self-efficacy beliefs. Conclusion: Our study identified several predictors of COVID-19 vaccine intention (e.g., safety, trust, risk perception, etc.) and helped to select the most relevant determinants/beliefs to target in an intervention to maximize the COVID-19 uptake. Where concerns and trust related to the COVID-19 vaccine are the most important target for future interventions, other determinants that were already positive (i.e., risk perception, attitudes, perceived norms, and self-efficacy) could be further confirmed.

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