Regression analysis was used to develop an in utero fetal weight model from a population of 392 predominantly middle-class white patients with certain menstrual histories. There was a gradual increase in fetal weight from 35 g at 10 weeks to 3,619 g at 40 weeks, with uniform variance of +/- 12.7% (1 standard deviation) throughout gestation. When tested against the estimated weights of 1,771 chromosomally normal fetuses between 14 and 21 weeks, the mean percent difference was 0.8% and the average absolute percent error was 3.3%. When compared with actual delivery data for 163 fetuses in the group, the mean percent difference was 0.8% and the average absolute percent error was 1.1%. These data are compared with other prenatal weight curves obtained at ultrasound and with data from several large postnatal weight studies.
Sonographic estimation of fetal weight in utero was performed in 167 live-born fetuses examined within one week of delivery. Regression models were based on measurements of abdominal circumference, head circumference, biparietal diameter, and femur length, both alone and in combination. The best results (1 S.D. = 7.5% of actual weight) were obtained by combining measurements of the fetal head, abdomen, and femur, most likely due to the strong linear relationship between femur length and crown-heel length.
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