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Background Neurological and psychiatric disorders are serious and expensive global public health problems. Therefore, exploring effective intervention technologies plays an important role in improving patients’ clinical symptoms and social functions, as well as reducing medical burden. Objective The aim of this study is to analyze and summarize the key new technologies and innovative development trends witnessed globally for neurological illness and psychiatric disorders by mining the relevant patent data. Methods A bibliometric analysis was conducted on patent applications, priority countries, main patentees, hot technologies, and other patent information on neurological and psychiatric disorders, revealing the current situation along with the trend of technology development in this field. Results In recent years, inventions and innovations related to neurological and psychiatric diseases have become very active, with China being the largest patent priority country. Of the top patent holders, Visicu (headquartered in the United States) is the leader. The distribution of patent holders in China remains relatively scattered, with no monopoly organization at present. Global technologies on neurological illness and psychiatric disorders are mainly concentrated around A61B (diagnosis, surgery, and identification). Conclusions This paper analyzed and summarized the key new technologies and global innovative development trends of neurological and psychiatric diseases by mining the relevant patent data, and provides practical references and research perspectives for the prevention and treatment of the aforesaid diseases.

Objective To investigate the proportion of registered cases relative to size, distribution characteristics, medication status, and management status of patients diagnosed with severe mental disorders (SMD) in Fuzhou. The medication status and management status were compared between patients in urban and non-urban areas to provide scientific evidence for improving SMD care, control, and treatment in primary health care institutions. Methods Data (case types, demographic data, distribution data, medication status, and management status, etc.) of patients diagnosed with SMD in 12 districts, counties, and prefectures in the urban and non-urban areas of Fuzhou City were collected from October 2017 to September 2018. Three distributions (population, local, and districts/counties) were used to describe the proportion of registered cases relative to size and clinical characteristics of diagnosed SMD. Chi squared (χ2) test was used to compare the severity in urban and non-urban areas. Results A total of 30,362 registered SMD patients were identified in Fuzhou City of which schizophrenia accounted for the highest number of cases (26,204, 86.31%), and paranoid psychosis had the least number of cases (47, 0.15%). Moreover, approximately half of SMD patients were 18 to 44 years old (45.38%). Close to one third of patients were farmers (30.23%), had a primary school or lower education level (54.17%), were poor, with most below the poverty line (55.35%). The proportion of diagnosed SMD relative to size was highest in Minqing County (0.53%) and lowest in Mawei District (0.38%). A total of 22,989 (75.72%) of the patients were taking medications, and only 17,509 (57.67%) were taking medications regularly. Moreover, the percentage of cases taking medications and those taking medications regularly were higher in urban areas than in non-urban areas (P<0.05). A total of 3065 patients were registered for management (10.09%). The managed proportion of SMD cases was higher in the urban areas than in the non-urban areas (P < 0.05). Conclusion Schizophrenia is a key disease for comprehensive care and control of severe mental disorders in Fuzhou. The management of severe mental disorders should focus on poor groups with low educational backgrounds. Drug usage and management are better in urban areas than in non-urban areas, and thus management should be enhanced in non-urban areas. The medication management and case management of patients with severe mental disorders in Fuzhou need further improvements.

This study was designed to investigate the prevalence of short sleep duration in adolescents from middle school in Fuzhou, China and explore the association between short sleep duration and overweight/obesity. Nano-encapsulated vitamin D3 can improve sleep deprivation, thus reducing the prevalence of overweight and obesity. A total of 13063 students (male: 6,500; female: 6,553) from 18 schools were investigated in the study. Questionnaires focusing on short sleep duration and overweight or obesity related factors were collected. The subjects reported their own sleep duration. The body weight and height of each subject were measured by the qualified personnel. Logistic regression analysis was used to evaluate the effects of short sleep duration on overweight/obesity in school students. The rates of overweight and obesity were 12.1% and 7.1%, respectively. The prevalence of short sleep duration among teenagers was 82.8%. The majority of high school students (92.5%) suffered from short sleep duration. Compared with male children with a sleep duration of 8-10 h per day, the odds ratios (95% Cl) of overweight/obesity for those with a sleep duration of less than 6 h or 6-8 h, were 1.63 (1.25-2.13) and 1.06 (0.88-1.27), respectively, after adjusting social and demographic status, mental health and lifestyle factors, while for female children, the odds ratios were 1.38 (0.99-1.93) and 1.04 (0.79-1.35), respectively. A large number of adolescents suffered from short sleep duration. Short sleep duration is associated with higher odds of overweight/obesity in male children.

Abstract Background: This study was designed to investigate the prevalence of sleep deprivation and explore the association between sleep duration and overweight or obesity in adolescents from middle school in Fuzhou, China.Methods: Questionaires focusing on sleep duration and overweight or obesity related factors were collected. A generalized linear hybrid model was used to evaluate the effects of sleep duration on overweight or obesity in school students.Results: The overall rates of overweight and obesity were 12.1% and 7.1%, respectively. The prevalence of sleep deprivation among students was 82.8%. The majority of high school students (92.5%) suffered from insufficient sleep. Compared with male children with a sleep duration of over 8 hrs a day, the odds ratios (95% CI) of overweight/obesity for those with a sleep duration of less than 6 h or 6 - 8 h, were 1.63 (1.25-2.13) and 1.06 (0.88-1.27). After adjusting social and demographic status, mental health and lifestyle factors, the odds ratios of female children were 1.38(0.99-1.93) and 1.04 (0.79-1.35), respectively.Conclusions: A large number of adolescents suffered from insufficient sleep. Sleep duration was negatively correlated with overweight or obesity among male children.