Aim There is a lack of an overview of the factors associated with postacute COVID‐19 musculoskeletal symptoms. The aims of this study were as follows: 1‐ to evaluate the most frequent admission symptoms and the frequency of musculoskeletal symptoms in postacute COVID‐19 patients; and 2‐ to determine the related factors with the postacute COVID‐19 musculoskeletal symptoms. Methods A total of 280 postacute COVID‐19 patients (183 females, 97 males) were enrolled and divided into two groups: 1‐ patients whose musculoskeletal symptoms initiated with or were aggravated by COVID‐19 (n = 240); and 2‐ patients whose musculoskeletal symptoms did not change with COVID‐19 (n = 40). The variables were demographic and treatment data, symptoms on admission, postacute COVID‐19 symptoms, laboratory results (complete blood count, erythrocyte sedimentation rate, C‐reactive protein, ferritin and d ‐dimer), chest computed tomography findings and symptoms during acute COVID‐19. Results Most of the patients have fatigue (71.8%), spine pain (70.7%) and myalgia (60.7%). The most common pain region was the back (30.4%). The frequency of dyspnoea was 30%, cough 18.5% and chest pain 10.7%. Having any chronic disease ( P = .031), the duration of hospital stay ( P = .016), frequency of back pain during acute COVID‐19 ( P = .018), tomography findings and d ‐dimer ( P = .035) levels were significantly higher, and lymphocyte ( P = .024) levels were significantly lower in the patients whose symptoms began with or were aggravated by COVID‐19. Conclusion Back pain was the most frequent symptom on admission. The most common postacute COVID‐19 musculoskeletal symptoms were fatigue, spine pain and myalgia. Lower lymphocyte and higher d ‐dimer levels, the presence of COVID‐19 findings in tomography and back pain during acute COVID‐19 infection, higher duration of hospital stay and having chronic diseases were related to post‐COVID‐19 musculoskeletal symptoms.
Objective: The aim of this randomized controlled study was to evaluate the efficacy of oral native type II collagen treatment on the symptoms and biological markers of cartilage degradation, when given concomitantly with acetaminophen in patients with knee osteoarthritis. Materials and Methods:Thirty-nine patients diagnosed with knee osteoarthritis were included and randomly distributed into two groups: one treated with 1500 mg/day of acetaminophen (group AC; n=19) and the other treated with 1500 mg/day of acetaminophen plus 10 mg/day of native type II collagen (group AC+CII; n=20) for 3 months. Visual Analogue Scale (VAS) at rest and during walking, Western Ontario McMaster (WOMAC) pain, WOMAC function, and Short Form-36 (SF-36) scores, were recorded. Coll2-1, Coll2-1NO2 and Fibulin-3 levels were quantified in urine as biomarkers of disease progression. ClinicalTrials.gov: NCT02237989.Results: After 3 months of treatment, significant improvements compared to baseline were reported in joint pain (VAS walking), function (WOMAC) and quality of life (SF-36) in the AC+CII group, while only improvements in some subscales of the SF-36 survey and VAS walking were detected in the AC group. Comparisons between the groups revealed a significant difference in VAS walking score in favour of the AC+CII group as compared to AC group. Biochemical markers of cartilage degradation in urine did not significantly improve in any of the groups. Conclusion:All in all, these results suggest that native type II collagen treatment combined with acetaminophen is superior to only acetaminophen for symptomatic treatment of patients with knee osteoarthritis.
OBJECTIVE:The aim of this placebo-controlled study was to evaluate the effects of pulsed and continuous ultrasound treatments combined with splint therapy on patients with mild and moderate idiopathic carpal tunnel syndrome.METHODS:The study included 46 carpal tunnel syndrome patients who were randomly divided into 3 groups. The first group (n = 15) received a 0 W/cm2 ultrasound treatment (placebo); the second group (n = 16) received a 1.0 W/cm2 continuous ultrasound treatment and the third group (n = 15) received a 1.0 W/cm2 1:4 pulsed ultrasound treatment 5 days a week for a total of 15 sessions. All patients also wore night splints during treatment period. Pre-treatment and post-treatment Visual Analogue Scale, Symptom Severity Scale and Functional Status Scale scores, median nerve motor conduction velocity and distal latency and sensory conduction velocities of the median nerve in the 2nd finger and palm were compared. Clinicaltrials.gov: NCT02054247.RESULTS:There were significant improvements in all groups in terms of the post-treatment Functional Status Scale score (p<0.05 for all groups), Symptom Severity Scale score (first group: p<0.05, second group: p<0.01, third group: p<0.001) and Visual Analogue Scale score (first and third groups: p<0.01, second group: p<0.001). Sensory conduction velocities improved in the second and third groups (p<0.01). Distal latency in the 2nd finger showed improvement only in the third group (p<0.01) and action potential latency in the palm improved only in the second group (p<0.05).CONCLUSION:The results of this study suggest that splinting therapy combined with placebo and pulsed or continuous ultrasound have similar effects on clinical improvement. Patients treated with continuous and pulsed ultrasound showed electrophysiological improvement; however, the results were not superior to those of the placebo.
The prevalence of musculoskeletal problems in pregnancy can vary according to trimester. Early diagnosis and treatments are important to prevent the development of chronic problems. This study was conducted to identify the most common musculoskeletal problems according to trimester, experienced by pregnant women.Material and methods: A total of 120 pregnant women who admitted to physical medicine and rehabilitation clinic, evaluated retrospectively in this study. Application complaints, the diagnosis and the trimester of the pregnant women and also age, weight, height, number of pregnancy, working status, presence of secondary disease were recorded.Results: In the first trimester, the most experienced musculoskeletal problems were low back pain (26.3%), pelvic girdle pain (26.3%) and carpal tunnel syndrome (26.3%). The most frequent problem in the second trimester was lower back pain (43.6%) followed by cramp (32.7%) and pelvic girdle pain (30.9%). Finally, in the third trimester, low back pain (34.8%), cramp (32.6%) and pedal edema (32.6%) were the most reported problems. Conclusion:The prevalence of musculoskeletal problems in pregnancy can vary according to socio-cultural and environmental factors. Determining the most common musculoskeletal problems experienced in pregnancy in a specific region is important for early diagnosis, increasing quality of life and preventing the development of chronic disorders.
ÖzHerpes zoster enfeksiyonu tanılı 78 yaşında erkek hastanın sol elinde renk değişikliği, tutukluk, şişlik ve yanıcı ağrısı mevcuttu. El eklemleri ağrılı, eklem hareket açıklığı azalmış ve hiperpigmente, sol C5-C6 dermatomal bölgede maküler lezyonlar tespit edildi. Medikal ve fizik tedavi programı sonrası semptomlar anlamlı şekilde azaldı. Kompleks bölgesel ağrı sendromu (KBAS) şişlik, eklemlerde tutukluk, vasküler instabilite, distrofik deri değişiklikleriyle ağrılı bir bozukluktur. Semptomlar sıklıkla travma, inme, cerrahi, miyokard enfarktüs, kırık, kanser sonrası görülür. Bu olguda kompleks bölgesel ağrı sendromunun olağandışı bir nedeni olan herpes zoster bildirilmiştir. Bugüne kadar sadece birkaç olgu rapor edilmiştir. Bu olgu sunumunda KBAS'nin birçok durumun komplikasyonu olarak görülebileceği vurgulanmaktadır. Erken teşhis ve tedavi, olumlu sonuçlara yol açmaktadır. Anahtar kelimeler: Kompleks bölgesel ağrı sendromu, herpes zoster, rehabilitasyon A 78-year-old male patient, diagnosed with herpes zoster infection, had color change, stiffness, swelling and burning pain on his left hand. Hand joints were painful, joint range of motion decreased and hyperpigmented, macular lesions on the left C5-C6 dermatome region was determined. After the medical and physical therapy programme, symptoms decreased significantly. Complex regional pain syndrome (CRPS) is a painful disorder with swelling, stiffness in joints, vascular instability, and dystrophic skin changes. Symptoms most commonly occur after trauma, stroke, surgery, myocardial infarction, fracture, cancer. In this case, an unusual cause of complex regional pain syndrome, herpes zoster, was reported. Only a few cases have been reported to date. In this case report, it is emphasized that CRPS can occur as a complication of many conditions. Early diagnosis and appropriate treatment lead to better outcomes.
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