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Astract: Odontogenic myxoma is a comparatively rare lesion of the jaw bone. A case of odontogenic myxoma occurring in the mandible of a young girl that was treated by two-stage surgery to preserve the form of the mandible is presented. A 12-year-old girl was referred to our hospital because of a painless swelling in the right lower molar region. Radiographic examinations revealed multilocular radiolucency with a fine"soap bubble" appearance, accompanied by impacted second and third molars, at presentation.