No abstract

Monodisperse water-stable silica functionalization of upconversion nanoparticles are important for their applications in bio-imaging and bio-sensing. Here, we report on the uniform silica coating of NaYF4:Yb,Er,Tm upconversion nanoparticles (UCNPs) with a controlled thickness (3-16 nm) through a modifi ed reverse microemulsion approach. We show that the molar ratio between tetraethylorthosilicate (TEOS) and UCNPs is important to tune the resulting thickness of silica, which can be controlled via simple increase of the concentration of UCNPs while maintaining the TEOS concentration constant. Our results show that those silica-coated upconversion nanoparticles are stable at pH = 7 sodium chloridefree solution, important for their bio-applications.