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Guayulin A (1) is a principal component of the resin of the Mexican rubber plant, guayule [Parthen turn argentatum (Gray)], a common desert shrub in the southwestern United States. Guayule was the main source of rubber in the U.S. during the early part of this century, before being supplanted by rubber from Asian rubber-tree plantations and later by synthetic rubbers. The projected future of natural rubber needs, production, and prices, as well as national security considerations, have promoted a concerted program, sponsored by both government and industry, to reestablish a domestic U.S. rubber industry based on guayule (1). Annual production of guayule rubber is expected to be 500-1500 million pounds by the year 2000

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