Children who develop first episode psychosis during adolescence differ from children with normal development. The premorbid internalizing state is common to AG but social competencies and school problems are the most affected areas in EOS when compared to the AG. It is hypothesized that both EOS and AG can be considered as the expression of a previous vulnerability.

Nonconvulsive status epilepticus can be confused with psychiatric disorders. Inappropriate drug treatment can represent a precipitating factor. We describe two patients with idiopathic generalized epilepsy in whom nonconvulsive status epilepticus, aggravated by carbamazepine, was misdiagnosed as psychiatric disorder. A 14-year-old girl experienced a tonic-clonic seizure at age 12 years preceded by monthly episodes of confusion with awkward behavior since age 9 years. She was treated with carbamazepine, and the episodes of confusion became more frequent, leading to a diagnosis of dissociative disorder. An electroencephalogram during one of these episodes revealed nonconvulsive status epilepticus. Substitution of carbamazepine with valproic acid controlled the episodes of status epilepticus. A 23-year-old woman presented at age 16 years with a tonic-clonic seizure. Since early adolescence, she had had episodes of depressive mood, worsening of school performances, and facial tics. Carbamazepine treatment caused worsening of the depressive episodes and facial tics. An electroencephalogram during a typical episode revealed nonconvulsive status epilepticus. Carbamazepine substitution with valproate led to seizure freedom and behavioral improvement. Nonconvulsive status epilepticus should be suspected and searched for in patients with epileptic seizures and ictal or fluctuating behavioral disorders.

ResumenObjetivoDescribir el estado premórbido de la esquizofrenia de inicio temprano (EIT).MétodosSe comparó a 23 adolescentes con EIT con un grupo de control sano (GC) y con un grupo de pacientes anoréxicos (GA). El estado premorbido se estudió por medio de la CBCL y los datos obtenidos se analizaron utilizando ANOVA y la prueba de la t.ResultadosDurante el periodo premórbido, la EIT mostró puntuaciones significativamente más altas en todas las escalas en relación con el GC y sólo en algunas (social, problemas de pensamiento y atención, y competencias escolares) en relación con el GA.ConclusionesLos niños que desarrollan psicosis de primer episodio durante la adolescencia difieren de los niños con desarrollo normal. El estado internalizador premórbido es común al GA, pero las competencias sociales y los problemas escolares son las áreas más afectadas en la EIT cuando se compara el GA. Se plantea la hipótesis de que tanto la EIT como el GA se pueden considerar como la expresión de una vulnerabilidad previa.