helpful to increase the participation and the understanding of chemopreventive approaches.

Introduction !Women have a 10 % risk of developing breast cancer at some stage in their life. This makes breast cancer the most common type of cancer found in women and the most common cause of death for women between the ages of 35 and 55 years. In Germany, around 58 000 women develop breast cancer every year, and approximately 20 000 die of it [1]. The treatment options and the characteristics determining the choice of therapy in patients with primary advanced breast cancer are Abstract !

Aim: A prospective clinical study was done to see whether it is possible to reduce the rate of reexcisions using digital breast tomosynthesis (DBT) compared commercial FFDM. Material and Method: Between 1/2011 and 5/ 2011 we diagnosed an invasive breast cancer (BI-RADS 5) in 100 patients. After histological verification we performed breast-conserving therapy with intraoperative imaging using one of 2 different systems: 1.

We evaluated the diagnostic accuracy and complications of digital subtraction angiography (DSA) in a series of clinical trials conducted on patients primarily with cerebral vascular disease and those evaluated before and after surgery or percutaneous transluminal angioplasty. Double-blind studies of the carotid-vertebral arteries of 300 of the 2,200 patients using DSA imaging and a variety of ionic and nonionic contrast agents showed that although subjects tolerated the injection of nonionic contrast better than ionic, nonionic contrast administration did not lead to better image quality. Of 764 patients receiving ionic contrast media, 3.3% had mild-to-serve adverse reactions; of 350 injected with nonionic contrast agents, 1.7% had mild-to-severe adverse reactions. If the sole consideration is safety, use of ionic contrast media is justified.

Around 55 000 women develop breast cancer and 20 000 women die of it in Germany every year [1]. The individual prognosis of patients with breast cancer depends in the first instance on the extent of disease at the time of diagnosis and on the implemented treatment plan [2][3][4]. According to both European treatment recommendations and the German interdisciplinary S3 Guideline for the Diagnosis, Treatment and Follow-up of Breast Cancer, at least 70 % of all breast Abstract ! Introduction: This study aimed to compare the accuracy of sonography versus digital breast tomosynthesis to locate intramammary marker clips placed under ultrasound guidance. Patients and Methods: Fifty patients with suspicion of breast cancer (lesion diameter less than 2 cm [cT1]) had ultrasound-guided core needle biopsy with placement of a marker clip in the center of the tumor. Intramammary marker clips were subsequently located with both sonography and digital breast tomosynthesis. Results: Sonography detected no dislocation of intrammammary marker clips in 42 of 50 patients (84 %); dislocation was reported in 8 patients (16 %) with a maximum dislocation of 7 mm along the x-, y-or z-axis. Digital breast tomosynthesis showed accurate placement without dislocation of the intramammary marker clip in 48 patients (96 %); 2 patients (4 %) had a maximum clip dislocation of 3 mm along the x-, y-or z-axis (p < 0.05). Conclusion: The use of digital breast tomosynthesis could improve the accuracy when locating intramammary marker clips compared to sonography and could, in future, be used to complement or even completely replace sonography.