The use of commercially produced fibrin glue, successfully used for many surgical procedures in European operating theatres, is prohibited in the USA due to FDA regulations. In this presentation the authors demonstrate the extraction of fibrinogen from the patient's own blood, thus avoiding possible viral contamination and allergenisity. Clinical and experimental applications are demonstrated.
It has recently become clinically feasible to extract highly concentrated fibrinogen from the patient's own blood. In combination with commercial thrombin this fibrinogen/thrombin compound can be used as tissue adhesive, hemostatic agent and intravascular embolizer. In this presentation the authors describe a new end-to-side and side-to-side microanastomosis using this autologous "fibrin glue" (Fibrinkleber) in stead of suture material. The advantages of the new technique consist of: • Simplicity • Greatly reduced OR time • Increased patency rate • Can be done without operating microscope
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