Relevance. In the context of the ongoing pandemic of new coronavirus infection, the development and implementation of new methods for medical (pulmonary) rehabilitation of patients is an urgent scientific and practical task. Intention. To assess the effectiveness and substantiate the possibility of using a new physiotherapeutic technology based on bioacoustic stimulation of the respiratory system with high-intensity low-frequency sounds in the comprehensive medical rehabilitation of patients with coronavirus pneumonia. Methodology. A randomized controlled open parallel clinical trial of 28 patients was conducted to assess effectiveness of medical rehabilitation after coronavirus pneumonia. Results and Discussion. Changes in external respiration indicators, psychological status and severity of post-traumatic stress disorders statistically significantly differed in the intervention and control groups before and after the course of rehabilitation. Therefore, bioacoustic stimulation of the respiratory system as part of comprehensive medical rehabilitation program after coronavirus pneumonia significantly increases its effectiveness. Conclusion. Bioacoustic stimulation of the respiratory system with high-intensity low-frequency sounds can be recommended as an effective physical method for inclusion in the comprehensive medical rehabilitation program for patients recovered from coronavirus pneumonia.